Anti-apoptotic proteins, apoptotic and proliferative parameters and their prognostic significance in cervical carcinoma

• Published in: European journal of cancer (1990) Vol. 37; no. 9; pp. 1104 - 1110
• Main Authors: Liu, S.S, Tsang, B.K, Cheung, A.N.Y, Xue, W.C, Cheng, D.K.L, Ng, T.Y, Wong, L.C, Ngan, H.Y.S
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.06.2001; Elsevier
• Subjects: Adult; Aged; Aged, 80 and over; Apoptosis - physiology; Apoptotic (AI) and mitotic indices (MI); Biological and medical sciences; Carcinoma, Squamous Cell - pathology; Cell Division; Cervical carcinoma and prognosis; Female; Female genital diseases; Gynecology. Andrology. Obstetrics; Humans; Immunohistochemical staining; Immunohistochemistry; In Situ Nick-End Labeling - methods; Inhibitor of apoptotic protein (IAP); Ki-67 Antigen - analysis; Ki-67 index; Medical sciences; Middle Aged; Mitosis - physiology; Prognosis; Retrospective Studies; Survival Analysis; Terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuracil triphosphate (dUTP) nick-end labelling (TUNEL); Tumors; Uterine Cervical Neoplasms - pathology; Cervical carcinoma and prognosis; Ki-67 index; Inhibitor of apoptotic protein (IAP); Terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuracil triphosphate (dUTP) nick-end labelling (TUNEL); Immunohistochemical staining; Apoptotic (AI) and mitotic indices (MI); Human; Immunohistochemistry; Cell proliferation; Correlation; Carcinoma; Prognosis; Stage classification; Tumoral marker; Uterine cervix; Malignant tumor; Gene expression; Female genital diseases; Female; Uterine cervix diseases; Apoptosis

The inhibitor of apoptosis proteins (IAP) suppress apoptosis induced by a variety of stimuli. The aims of this study were to: (a) compare the expression of X-linked IAP (Xiap) and Human IAP-2 (Hiap-2) in cervical carcinoma cells and normal cervix, (b) determine the correlation between IAP expression...