Dynamic evolution of D-dimer level in cerebrospinal fluid predicts poor outcome in patients with spontaneous intracerebral hemorrhage combined with intraventricular hemorrhage

Highlights • Discovered strong correlation between cerebrospinal fluid D-dimer level and Graeb score. • Discovered continuous trend of cerebrospinal fluid D-dimer level predicts patient 30 day mortality. • Discovered early phase cerebrospinal fluid D-dimer level predicts patient 30 day mortality. •...

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Bibliographic Details
Published inJournal of clinical neuroscience Vol. 29; pp. 149 - 154
Main Authors Chen, Chih-Wei, Wu, En-Hsuan, Huang, Judy, Chang, Wen-Tsan, Ao, Kam-Hou, Cheng, Tain-Junn, Yang, Wuyang
Format Journal Article
LanguageEnglish
Published Scotland Elsevier Ltd 01.07.2016
Subjects
Adult
Aged
Biomarkers - cerebrospinal fluid
Cerebral Ventricles
Cohort Studies
Cost-Benefit Analysis
CSF
D-dimer
Female
Fibrin Fibrinogen Degradation Products - cerebrospinal fluid
Humans
Intracerebral hemorrhage
Intracranial Hemorrhages - cerebrospinal fluid
Intracranial Hemorrhages - diagnostic imaging
Intracranial Hemorrhages - mortality
Intraventricular hemorrhage
Male
Middle Aged
Neurology
Prognosis
Prospective Studies
Survival Analysis
Tomography, X-Ray Computed
Treatment Outcome
D-dimer
Intraventricular hemorrhage
Intracerebral hemorrhage
CSF
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Summary:Highlights • Discovered strong correlation between cerebrospinal fluid D-dimer level and Graeb score. • Discovered continuous trend of cerebrospinal fluid D-dimer level predicts patient 30 day mortality. • Discovered early phase cerebrospinal fluid D-dimer level predicts patient 30 day mortality. • Concluded that cerebrospinal fluid F D-dimer level is a potential surrogate marker of intraventricular hemorrhage severity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2015.10.036