Inflammatory trigeminal nerve and tract lesions associated with inferior alveolar nerve anaesthesia

Abstract Inferior alveolar nerve blocks are commonly performed for dental anaesthesia. The procedure is generally safe with a low rate of complications. We report a patient with a reproducible, delayed-onset sensory deficit associated with contrast-enhancing lesions in the trigeminal nerve, pons and...

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Bibliographic Details
Published inJournal of clinical neuroscience Vol. 20; no. 11; pp. 1608 - 1610
Main Authors Blair, N.F, Parratt, J.D.E, Garsia, R, Brazier, D.H, Cremer, P.D
Format Journal Article
LanguageEnglish
Published Scotland Elsevier Ltd 01.11.2013
Subjects
Anesthesia, Dental - adverse effects
Anesthesia, Dental - methods
Anesthetics, Local - adverse effects
Anti-Inflammatory Agents - therapeutic use
Brain - pathology
Delayed hypersensitivity
Humans
Inferior alveolar nerve
Inflammation - chemically induced
Inflammation - drug therapy
Local anesthesia
Magnetic resonance imaging
Male
Mandibular Nerve - drug effects
Middle Aged
Nerve Block - adverse effects
Neurology
Trigeminal nerve
Trigeminal Nerve - pathology
Trigeminal nuclei
Delayed hypersensitivity
Magnetic resonance imaging
Trigeminal nerve
Inferior alveolar nerve
Trigeminal nuclei
Local anesthesia
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Summary:Abstract Inferior alveolar nerve blocks are commonly performed for dental anaesthesia. The procedure is generally safe with a low rate of complications. We report a patient with a reproducible, delayed-onset sensory deficit associated with contrast-enhancing lesions in the trigeminal nerve, pons and medulla following inferior alveolar nerve local anaesthesia. We propose that this previously undescribed condition is a form of Type IV hypersensitivity reaction.
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ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2012.10.027