Endogenous methicillin resistant staphylococcus aureus as a source of post-operative surgical site infections

• Published in: Journal of the Pakistan Medical Association Vol. 71; no. 1(A); pp. 94 - 12
• Main Authors: Farwa, Umme, Aftab, Irum, Kaleem, Fatima, Khattak, Mehnaz, Iqbal, Mariam Danish, Butt, Tariq, Abbasi, Shahid Ahmad
• Format: Journal Article
• Language: English
• Published: Pakistan Knowledge Bylanes 01.01.2021; Pakistan Medical Association
• Subjects: Anti-Bacterial Agents - therapeutic use; Complications and side effects; Cross Infection - drug therapy; Cross-Sectional Studies; Drug resistance in microorganisms; Female; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Pakistan - epidemiology; Risk factors; Staphylococcal Infections - drug therapy; Staphylococcal Infections - epidemiology; Staphylococcus aureus infections; Surgical Wound Infection - drug therapy; Surgical Wound Infection - epidemiology; Surgical wound infections; Pakistan; Endogenous MRSA, Surgical site infection, Surveillance, Antibiotics resistance
• ISSN: 0030-9982
• DOI: 10.47391/JPMA.649

To determine frequency of Endogenous Methicillin Resistant Staphylococcus aureus (MRSA) in pre-operative patients and its frequency in Surgical Site Infections (SSIs) post operatively. It was a descriptive cross sectional conducted at Department of Microbiology, Fauji Foundation Hospital Rawalpindi (FFH), Pakistan. Samples were collected from 1st November-31st May 2018. Total 75 samples were collected during the period. Consecutive non-probability sampling technique was utilized. Specimens were collected from nose, axilla and groin of preoperative patients. Methicillin Resistant Staphylococcus aureus was identified if only isolated from these sites. Patients were followed till his/her discharge from the hospital and if they developed infection post operatively, pus specimen from infected site was also collected and identified. Out of 75 specimen preoperatively, 11(14.7%) were identified as endogenous MRSA. From these, 33(44%) developed Surgical site infections (SSIs), among them 19(57%) were MRSA (09 endogenous, 10 exogenous), 7(21.2%) were Escherichia coli, 3(9.1%) were Klebsiella pneumoniae, 3(9.1%) were Enterococcus faecalis and 1(3%) was Methicillin Sensitive Staphylococcus aureus. The results of this study determined that Endogenous Methicillin Resistant Staphylococcus aureus (MRSA) could be isolated from patients going for surgery if microbiological screening was done at the time of admission. This could prevent patients from Surgical Site Infection Post operatively by these endogenous MRSA. This search and wipe out strategy is able to curtail the events of outbreak, reduce hospital stay and decrease budget of the hospital by providing guidance in choice of empirical therapy for infection.