Modulation of raft domains in a lipid bilayer by boundary-active curcumin

The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered a...

Full description

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 50; no. 26; pp. 3427 - 3430
Main Authors Tsukamoto, Manami, Kuroda, Kenichi, Ramamoorthy, Ayyalusamy, Yasuhara, Kazuma
Format Journal Article
LanguageEnglish
Published England 04.04.2014
Subjects
Curcumin - chemistry
Lipid Bilayers
Membrane Microdomains
Online AccessGet full text

Cover

More Information
Summary:The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc47738j