Exercise-induced alterations in plasma concentrations of ghrelin, adiponectin, leptin, glucose, insulin, and cortisol in horses
Six Standardbred (STB) mares (11 ± 2 years, 521 ± 77 kg; means ± SD) performed an exercise trial (EX) where they underwent an incremental exercise test (GXT) as well as a parallel control trial (CON) to test the hypothesis that short-term, high intensity exercise would alter plasma concentrations of...
Saved in:
Published in | The veterinary journal (1997) Vol. 173; no. 3; pp. 532 - 540 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.05.2007
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Six Standardbred (STB) mares (11
±
2 years, 521
±
77
kg; means
±
SD) performed an exercise trial (EX) where they underwent an incremental exercise test (GXT) as well as a parallel control trial (CON) to test the hypothesis that short-term, high intensity exercise would alter plasma concentrations of glucose, leptin, adiponectin, ghrelin, insulin and cortisol. Plasma samples were taken before (0
min), during (last 10
s at 6, 8
m/s, and the velocity eliciting VO
2max), and after exercise (2, 10, 30, 60
min; 12 and 24
h post-GXT). A second set of blood samples was collected before and after an afternoon meal given at 1515
h (at 1500, 1514, 1530, and 1545
h). Data were analyzed using ANOVA for repeated measures and Tukey’s test.
During the GXT, there were no changes (
P
>
0.05) in the plasma concentrations of glucose, leptin, adiponectin or ghrelin. However, there was a 29% increase (
P
<
0.05) in mean plasma cortisol concentration and a 35% decrease (
P
<
0.05) in mean plasma insulin concentration. Substantial increases (
P
<
0.05) in the mean plasma concentrations of glucose and cortisol of 36% and 102%, respectively, were seen in the EX trial during the first 60
min post-GXT. Plasma leptin concentration, measured at the 24
h post-GXT time point, was 20% lower (
P
<
0.05) during the EX trial compared with the parallel time point in the standing control (CON) trial. Plasma ghrelin concentration was 37% lower (
P
<
0.05) in the EX trial compared with CON before and after the afternoon meal, but was 43% higher (
P
<
0.05) 12
h post-GXT. There were no differences between EX and CON for plasma concentrations of insulin or adiponectin during recovery. It was concluded that short-term high intensity exercise alters plasma leptin and ghrelin concentrations in STB mares post-exercise, which may signal the exercised animals to alter energy intake. |
---|---|
Bibliography: | http://dx.doi.org/10.1016/j.tvjl.2006.01.003 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-3 content type line 23 |
ISSN: | 1090-0233 1532-2971 |
DOI: | 10.1016/j.tvjl.2006.01.003 |