Research Ethics in the Era of Personalized Medicine Updating Science’s Contract with Society

With the completed sequence of the human genome has come the prospect of substantially improving the quality of life for millions through personalized medicine approaches. Still, any advances in this direction require research involving human subjects. For decades science and ethics have enjoyed an...

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Bibliographic Details
Published inCommunity genetics Vol. 13; no. 6; pp. 378 - 384
Main Authors Meslin, Eric M., Cho, Mildred K.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 01.01.2010
Subjects
Ethics, Research
Human Genome Project
Humans
Original Paper
Precision Medicine
Quality of life
Research ethics
Societies
Special Topic Section: The Age of Personal Genomics. Editor: Timothy Caulfield (Edmonton
Special Topic Section: The Age of Personal Genomics. Editor: Timothy Caulfield (Edmonton, Alta.). Original Paper
Personalized medicine
Research ethics
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Summary:With the completed sequence of the human genome has come the prospect of substantially improving the quality of life for millions through personalized medicine approaches. Still, any advances in this direction require research involving human subjects. For decades science and ethics have enjoyed an allegiance reflected in a common set of ethical principles and procedures guiding the conduct of research with human subjects. Some of these principles emphasize avoiding harm over maximizing benefit. In this paper we revisit the priority given to these ethical principles – particularly the principles that support a cautious approach to science – and propose a reframing of the ‘social contract’ between science and society that emphasizes reciprocity and meeting public needs.
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ISSN:1662-4246
1662-8063
1662-8063
DOI:10.1159/000319473