Age of onset and alcohol and cannabis use disorders among Mexican American young adults: Robust substance-specific effects of early use as a risk factor

We investigated the substance-specific and cross-substance risk associated with early onset (before age 15) of drunkenness and cannabis use in the subsequent development of alcohol (AUD) and cannabis use disorder (CUD) in Mexican American young adults. Survival analyses employed Cox proportional haz...

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Bibliographic Details
Published inJournal of ethnicity in substance abuse p. 1
Main Authors Tam, Christina C, Gilder, David A, Li, Libo, Karriker-Jaffe, Katherine J, Duhart Clarke, Sarah E, Ehlers, Cindy L
Format Journal Article
LanguageEnglish
Published England 01.08.2024
Subjects
alcohol use disorder
cannabis use disorder
survival analysis
cross-substance risk
age of onset
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Summary:We investigated the substance-specific and cross-substance risk associated with early onset (before age 15) of drunkenness and cannabis use in the subsequent development of alcohol (AUD) and cannabis use disorder (CUD) in Mexican American young adults. Survival analyses employed Cox proportional hazards models for AUD and CUD, separately. In cross-risk analyses, we modeled estimates for those participants reporting lifetime use of substances. Early onset of drunkenness and early onset of cannabis use were associated with shorter time to AUD and CUD, respectively, even after accounting for psychiatric disorders. While there were no cross-risk associations, adjusting for psychiatric disorders and early onset cannabis use attenuated the association of early drunkenness with AUD.
ISSN:1533-2659
DOI:10.1080/15332640.2022.2111388