Catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives
Phenols are widely used as starting materials in both industrial and academic society. Dearomatization reactions of phenols provide an efficient way to construct highly functionalized cyclohexadienones. The main challenge to make them asymmetric by catalytic methods is to control the selectivity whi...
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| Published in | Chemical Society reviews Vol. 45; no. 6; pp. 157 - 158 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
21.03.2016
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Phenols are widely used as starting materials in both industrial and academic society. Dearomatization reactions of phenols provide an efficient way to construct highly functionalized cyclohexadienones. The main challenge to make them asymmetric by catalytic methods is to control the selectivity while overcoming the loss of aromaticity. In this tutorial review, an up to date summary of recent progress in CADA reactions of phenol and aniline derivatives is presented.
In this tutorial review, an up to date summary of recent progress in catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives is presented. |
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| Bibliography: | Liming Zhang was born in Pingxiang, China, in 1972. He received his B.S. degree in chemistry from Nanchang University in 1993, his first Master's degree in organometallic chemistry with Professor Zhengzhi Zhang from Nankai University in 1996, and his second Master's degree in organic chemistry with Professor Michael P. Cava from the University of Alabama in 1998. He obtained his Ph.D. degree with Professor Masato Koreeda from the medicinal chemistry program at the University of Michigan in 2003 and then carried out a post-doctoral study with Professor Sergey A. Kozmin at the University of Chicago. He started his independent academic career as Assistant Professor at the Department of Chemistry, University of Nevada, Reno, in July of 2005 and continued at the University of California Santa Barbara in July of 2009. He is currently a Professor of Organic Chemistry. His research interests include late transition metal-catalyzed reactions, natural product synthesis and medicinal chemistry. Wen-Ting Wu was born in 1989 in Suzhou, Jiangsu province, China, and received her BS degree from Soochow University in 2012. She then joined Shanghai Institute of Organic Chemistry (SIOC) for her PhD degree under the supervision of Prof. Shu-Li You and Prof. Liming Zhang. Her research focused on the gold-catalyzed dearomatization reactions. Dr Shu-Li You received his BSc in chemistry from Nankai University in 1996. He obtained his PhD from Shanghai Institute of Organic Chemistry (SIOC) in 2001 under the supervision of Prof. Li-Xin Dai before doing postdoctoral studies with Prof. Jeffery W. Kelly at The Scripps Research Institute. From 2004, he worked at the Genomics Institute of the Novartis Research Foundation as a Principal Investigator before returning to SIOC in 2006. His research interests include asymmetric catalysis, synthetic methodology, natural product synthesis, as well as medicinal chemistry. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-2 ObjectType-Feature-2 |
| ISSN: | 0306-0012 1460-4744 |
| DOI: | 10.1039/c5cs00356c |