Fibromyalgia and the complex regional pain syndrome: similarities in pathophysiology and treatment

• Published in: Metabolism, clinical and experimental Vol. 59; pp. S37 - S40
• Main Author: Wurtman, Richard J
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2010
• Subjects: Complex Regional Pain Syndromes - drug therapy; Complex Regional Pain Syndromes - etiology; Complex Regional Pain Syndromes - physiopathology; Endocrinology & Metabolism; Fibromyalgia - drug therapy; Fibromyalgia - etiology; Fibromyalgia - physiopathology; Humans; Ketamine - therapeutic use

Abstract Although the pain of fibromyalgia usually is not preceded by an injury to the involved tissue, whereas that of the complex regional pain syndrome usually starts at a site of prior trauma or surgery, both disorders may share a common mechanism—pathologic sensitization of brain mechanisms tha...