The Effect of the PB2 Mutation 627K on Highly Pathogenic H5N1 Avian Influenza Virus Is Dependent on the Virus Lineage

• Published in: Journal of Virology Vol. 87; no. 18; pp. 9983 - 9996
• Main Authors: Long, Jason S, Howard, Wendy A, Núñez, Alejandro, Moncorgé, Olivier, Lycett, Samantha, Banks, Jill, Barclay, Wendy S
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.09.2013
• Subjects: Amino Acid Substitution; Animals; Asia; Avian influenza virus; Cell Line; Chickens; Europe; Genetic Diversity and Evolution; Genomic Instability; Glutamic Acid - genetics; Humans; Influenza A Virus, H5N1 Subtype - genetics; Influenza A Virus, H5N1 Subtype - isolation & purification; Influenza A Virus, H5N1 Subtype - physiology; Influenza in Birds - virology; Lysine - genetics; Mutagenesis, Site-Directed; Mutant Proteins - genetics; Mutant Proteins - metabolism; Mutation, Missense; Reverse Genetics; RNA Replicase - genetics; RNA Replicase - metabolism; Viral Proteins - genetics; Viral Proteins - metabolism; Virus Replication; Asia; Europe; Turkey; British Isles, England; Africa; China, People's Rep; China, People's Rep. Qinghai Prov., Qinghai L
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.01399-13

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