Antibiotics and antibiotic resistance gene dynamics in the composting of antibiotic fermentation waste - A review

•Composting can effectively remove most antibiotics in different AFW.•The knowledge on degradation pathways of antibiotics is limited.•The fate of ARGs shows various trends in AFW composting.•Biotic factors are core driving forces for ARGs variation.•ARGs proliferation in composts can be inhibited b...

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Published inBioresource technology Vol. 390; p. 129861
Main Authors Feng, Minmin, Liu, Yuanwang, Yang, Lie, Li, Zhaojun
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.12.2023
Subjects
Abiotic factor
antibiotic resistance
antibiotic resistance genes
antibiotics
Bacterial composition
Biotic factor
fermentation
Mobile genetic element
wastes
Bacterial composition
Mobile genetic element
Abiotic factor
Biotic factor
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Summary:•Composting can effectively remove most antibiotics in different AFW.•The knowledge on degradation pathways of antibiotics is limited.•The fate of ARGs shows various trends in AFW composting.•Biotic factors are core driving forces for ARGs variation.•ARGs proliferation in composts can be inhibited by controlling abiotic factors. Fate of antibiotics and antibiotic resistance genes (ARGs) during composting of antibiotic fermentation waste (AFW) is a major concern. This review article focuses on recent literature published on this subject. The key findings are that antibiotics can be removed effectively during AFW composting, with higher temperatures, appropriate bulking agents, and suitable pretreatments improving their degradation. ARGs dynamics during composting are related to bacteria and mobile genetic elements (MGEs). Higher temperatures, suitable bulking agents and an appropriate C/N ratio (30:1) lead to more efficient removal of ARGs/MGEs by shaping the bacterial composition. Keeping materials dry (moisture less than 30%) and maintaining pH stable around 7.5 after composting could inhibit the rebound of ARGs. Overall, safer utilization of AFW can be realized by optimizing composting conditions. However, further removal of antibiotics and ARGs at low levels, degradation mechanism of antibiotics, and spread mechanism of ARGs during AFW composting require further investigation.
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ISSN:0960-8524
1873-2976
1873-2976
DOI:10.1016/j.biortech.2023.129861