Time-dependent hormesis of chemical mixtures: A case study on sulfa antibiotics and a quorum-sensing inhibitor of Vibrio fischeri

Highlights • The time-dependent hormesis of SAs and B3O on bioluminescence was observed. • The six SAs had a similar hormesis effect on bioluminescence. • Hormesis effect of the mixture on bioluminescence varied with time. • B3O had a larger impact on the time-dependent hormesis than SAs.

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Bibliographic Details
Published inEnvironmental toxicology and pharmacology Vol. 41; pp. 45 - 53
Main Authors You, Ruirong, Sun, Haoyu, Yu, Yan, Lin, Zhifen, Qin, Mengnan, Liu, Ying
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.01.2016
Subjects
Aliivibrio fischeri - drug effects
Aliivibrio fischeri - growth & development
Aliivibrio fischeri - metabolism
Anti-Bacterial Agents - toxicity
Bacterial Proteins - metabolism
Benzofurans - toxicity
Chemical mixtures
Dihydropteroate Synthase - metabolism
Emergency
Gene Expression Regulation, Bacterial - drug effects
Hormesis
Quorum Sensing - drug effects
Quorum-sensing inhibitor
Repressor Proteins - metabolism
Sulfonamides
Sulfonamides - toxicity
Time-dependent
Toxicity Tests, Chronic
Trans-Activators - metabolism
Vibrio fischeri
Time-dependent
Hormesis
Sulfonamides
Quorum-sensing inhibitor
Chemical mixtures
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Summary:Highlights • The time-dependent hormesis of SAs and B3O on bioluminescence was observed. • The six SAs had a similar hormesis effect on bioluminescence. • Hormesis effect of the mixture on bioluminescence varied with time. • B3O had a larger impact on the time-dependent hormesis than SAs.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2015.10.013