Persistence of Hypersensitivity to Lethal Effect of Injected Calcium Chloride for Ten Generations of Rats Raised from Parathyroidectomized Mothers

The authors have reported that the LD sub(50) values for injected calcium chloride in the 3rd generation rats raised from mothers parathyroidectomized on the 15th day of gestation (15dPTx) were much lower than in normal offspring rats (Fujii et al., 1980). The effect of maternal environment on the p...

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Published inProceedings of the Japan Academy, Series B Vol. 59; no. 4; pp. 105 - 107
Main Authors FUJII, Tomoko, MORZMOTO, Shoji, YAMAMOTO, Nobuko
Format Journal Article
LanguageEnglish
Published The Japan Academy 1983
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Summary:The authors have reported that the LD sub(50) values for injected calcium chloride in the 3rd generation rats raised from mothers parathyroidectomized on the 15th day of gestation (15dPTx) were much lower than in normal offspring rats (Fujii et al., 1980). The effect of maternal environment on the phenotypic expression of the offspring in one generation has been the subject of many studies. However, there are a few reports on the effect of maternal influence over several generations. In this paper, the LD sub(50) values for calcium chloride is reported in the 4th generation offsprings of the 15dPTx-rats.
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ISSN:0386-2208
1349-2896
DOI:10.2183/pjab.59.105