Current challenges in identification of clinical characteristics and detection of COVID-19: A comprehensive review

• Published in: Measurement. Sensors Vol. 16; p. 100052
• Main Authors: More, Namdev, Ranglani, Deepak, Kharche, Shubham, Choppadandi, Mounika, Ghosh, Sumanta, Vaidya, Sumedh, Kapusetti, Govinda
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2021; The Authors. Published by Elsevier Ltd; Elsevier
• Subjects: Characteristics of COVID-19; Coronavirus; Diagnostic methods of COVID-19; Point of care device; RT-PCR; Coronavirus; Point of care device; Diagnostic methods of COVID-19; RT-PCR; Characteristics of COVID-19
• ISSN: 2665-9174; 2665-9174
• DOI: 10.1016/j.measen.2021.100052

World Health Organization (WHO) declares the COVID-19 outbreak as a pandemic. The newly emerging infection has caused around one million deaths worldwide and still counting. There is no specific treatment for the disease, and it can only contain by breaking the spread. So that early and rapid diagnosis of the infection is the only way to control the outbreak. The COVID-19 virus affects the human respiratory system and subsequently infects other vital organs. In consideration of the diagnosis, the present review focuses on the critical diagnostic approaches for COVID-19, including RT-PCR, Chest-CT scan, some biosensor-based systems, etc. Moreover, this review is a specific bird's eye view on recent developments on the point of care devices and related technologies. Additionally, it presented a small glimpse of the pathophysiology and structural aspects of COVID-19. Therefore, the current review can motivate and help the reader to develop cutting-edge diagnostic technologies for the early and rapid detection of the COVID-19. [Display omitted] •Summarize the available data on diagnosis tools of COVID 19 and their potential limitations•Discuss the pathophysiology of COVID-19 in human•Emphasis on rapid testing of COVID 19 to contain the disease•Disuses in details about various diagnosis methods of COVID 19•Suggested some potential alternatives for development of rapid and specific sensors/kits for COVID-19