Excess Deaths of Gastrointestinal, Liver, and Pancreatic Diseases During the COVID-19 Pandemic in the United States
Objectives: To evaluate excess deaths of gastrointestinal, liver, and pancreatic diseases in the United States during the COVID-19 pandemic. Methods: We retrieved weekly death counts from National Vital Statistics System and fitted them with a quasi-Poisson regression model. Cause-specific excess de...
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Published in | International journal of public health Vol. 68; p. 1606305 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Frontiers Media S.A
15.08.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Objectives:
To evaluate excess deaths of gastrointestinal, liver, and pancreatic diseases in the United States during the COVID-19 pandemic.
Methods:
We retrieved weekly death counts from National Vital Statistics System and fitted them with a quasi-Poisson regression model. Cause-specific excess deaths were calculated by the difference between observed and expected deaths with adjustment for temporal trend and seasonality. Demographic disparities and temporal-spatial patterns were evaluated for different diseases.
Results:
From March 2020 to September 2022, the increased mortality (measured by excess risks) for
Clostridium difficile
colitis, gastrointestinal hemorrhage, and acute pancreatitis were 35.9%; 24.8%; and 20.6% higher than the expected. For alcoholic liver disease, fibrosis/cirrhosis, and hepatic failure, the excess risks were 1.4–2.8 times higher among younger inhabitants than older inhabitants. The excess deaths of selected diseases were persistently observed across multiple epidemic waves with fluctuating trends for gastrointestinal hemorrhage and fibrosis/cirrhosis and an increasing trend for
C. difficile
colitis.
Conclusion:
The persistently observed excess deaths of digestive diseases highlights the importance for healthcare authorities to develop sustainable strategies in response to the long-term circulating of SARS-CoV-2 in the community. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Giuseppe Di Martino, G. d'Annunzio University of Chieti and Pescara, Italy This Original Article is part of the IJPH Special Issue “Public Health and Primary Care, is 1+1=1?” Edited by: Gabriel Gulis, University of Southern Denmark, Denmark These authors have contributed equally to this work Reviewed by: Sina Azadnajafabad, Tehran University of Medical Sciences, Iran |
ISSN: | 1661-8564 1661-8556 1661-8564 |
DOI: | 10.3389/ijph.2023.1606305 |