Recent advances in biological activities of lignin and emerging biomedical applications: A short review

As an abundant biopolymer, lignin gains interest owing to its renewable nature and polyphenolic structure. It possesses many biological activities such as antioxidant activity, antimicrobial activity, and biocompatibility. Studies are being carried out to relate the biological activities to the poly...

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Published inInternational journal of biological macromolecules Vol. 208; no. C; pp. 819 - 832
Main Authors Ullah, Irfan, Chen, Zebang, Xie, Yuxin, Khan, Shahin Shah, Singh, Seema, Yu, Changyuan, Cheng, Gang
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 31.05.2022
Elsevier
Subjects
Biological activities
Biomedical applications
Lignin
Lignin
Biomedical applications
Biological activities
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Summary:As an abundant biopolymer, lignin gains interest owing to its renewable nature and polyphenolic structure. It possesses many biological activities such as antioxidant activity, antimicrobial activity, and biocompatibility. Studies are being carried out to relate the biological activities to the polyphenolic structures. These traits present lignin as a natural compound being used in biomedical field. Lignin nanoparticles (LNPs) are being investigated for safe use in drug and gene delivery, and lignin-based hydrogels are being explored as wound dressing materials, in tissue engineering and 3D printing. In addition, lignin and its derivatives have shown the potential to treat diabetic disease. This review summarizes latest research results on the biological activities of lignin and highlights potential applications exampled by selective studies. It helps to transform lignin from a waste material into valuable materials and products.
Bibliography:ObjectType-Article-2
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AC02-05CH1123
USDOE Office of Science (SC), Biological and Environmental Research (BER)
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2022.03.182