The human basophil: a new appreciation of its role in immune responses

• Published in: Blood Vol. 96; no. 13; pp. 4028 - 4038
• Main Authors: Falcone, Franco H., Haas, Helmut, Gibbs, Bernhard F.
• Format: Journal Article
• Language: English
• Published: Washington, DC Elsevier Inc 15.12.2000; The Americain Society of Hematology
• Subjects: Adult; Allergens - immunology; Allergic diseases; Antibodies, Monoclonal - immunology; Basophils - drug effects; Basophils - metabolism; Basophils - physiology; Biological and medical sciences; Calcium - physiology; Calcium Signaling - drug effects; Cell Differentiation; Cell Lineage; Cell Separation - methods; Chemotaxis, Leukocyte; Cytokines - pharmacology; Cytoplasmic Granules - metabolism; Fetal Blood - cytology; Forecasting; Fundamental and applied biological sciences. Psychology; Fundamental immunology; General aspects; Growth Substances - pharmacology; Helminthiasis - immunology; Helminthiasis - pathology; Hematopoietic Cell Growth Factors - pharmacology; Histamine Release - drug effects; Humans; Hypersensitivity - immunology; Hypersensitivity - pathology; Hypersensitivity, Delayed - immunology; Hypersensitivity, Delayed - pathology; Hypersensitivity, Immediate - immunology; Hypersensitivity, Immediate - pathology; Immunobiology; Immunoglobulin E - immunology; Immunopathology; Infant, Newborn; Inflammation - immunology; Inflammation - pathology; Interleukin-13 - metabolism; Interleukin-3 - pharmacology; Interleukin-3 - physiology; Interleukin-4 - metabolism; Mast Cells - immunology; Mast Cells - metabolism; Medical sciences; Mitogen-Activated Protein Kinase 1 - physiology; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases - physiology; Models, Immunological; Myeloid cells: ontogeny, maturation, markers, receptors; Phosphatidylinositol 3-Kinases - physiology; Phosphorylation; Polynuclears; Protein Kinase C - physiology; Protein Kinases - physiology; Protein Processing, Post-Translational; Receptors, IgE - physiology; Signal Transduction; Tumor Cells, Cultured; Human; Immunopathology; Allergy; Protein kinase C; Immune response; Pathophysiology; Enzyme; Transferases; IgE; Cytokine; Granulocyte; Immunoglobulin receptor; Interleukin 13; Review; Basophil; Signal transduction; Interleukin 4; Interleukin 3; Animal; Growth factor; Biological receptor
• ISSN: 0006-4971; 1528-0020
• DOI: 10.1182/blood.V96.13.4028