Treatment of gastric varices with partial splenic embolization in a patient with portal vein thrombosis and a myeloproliferative disorder

Therapeutic options for gastric variceal bleeding in the presence of extensive portal vein thrombosis associated with a myeloproliferative disorder are limited.We report a case of a young woman who presented with gastric variceal bleeding secondary to extensive splanchnic venous thrombosis due to a...

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Published inWorld journal of gastroenterology : WJG Vol. 20; no. 39; pp. 14495 - 14499
Main Authors Gianotti, Robert, Charles, Hearns, Hymes, Kenneth, Chandarana, Hersh, Sigal, Samuel
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 21.10.2014
Subjects
Adult
Case Report
embolization
Embolization, Therapeutic - methods
Esophageal and Gastric Varices - diagnosis
Esophageal and Gastric Varices - etiology
Esophageal and Gastric Varices - therapy
Female
Gastric
Gastrointestinal Hemorrhage - diagnosis
Gastrointestinal Hemorrhage - etiology
Gastrointestinal Hemorrhage - therapy
Humans
Janus Kinase 2 - genetics
Magnetic Resonance Imaging
Mutation
Myelo
Myeloproliferative Disorders - complications
Myeloproliferative Disorders - diagnosis
Myeloproliferative Disorders - enzymology
Myeloproliferative Disorders - genetics
Myeloproliferative Disorders - therapy
Partial
Portal Vein
splenic
Splenic Artery
Treatment Outcome
varices
Venous Thrombosis - diagnosis
Venous Thrombosis - drug therapy
Venous Thrombosis - etiology
Janus kinase 2, Portal hypertension
Myeloproliferative disorder
Partial splenic embolization
Portal vein thrombosis
Gastric varices
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Summary:Therapeutic options for gastric variceal bleeding in the presence of extensive portal vein thrombosis associated with a myeloproliferative disorder are limited.We report a case of a young woman who presented with gastric variceal bleeding secondary to extensive splanchnic venous thrombosis due to a Janus kinase 2 mutation associated myeloproliferative disorder that was managed effectively with partial splenic embolization.
Bibliography:Robert Gianotti;Hearns Charles;Kenneth Hymes;Hersh Chandarana;Samuel Sigal;Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States;New York University School of Medicine, New York, NY 10022, United States
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
Telephone: +1-617-6672136 Fax: +1-617-6672767
Author contributions: All the authors contributed to conception and design, acquisition of data, or analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version to be published.
Correspondence to: Robert Gianotti, MD, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Dana 501, Boston, MA 02215, United States. rgianott@bidmc.harvard.edu
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i39.14495