Intranasal Prophylaxis with CpG Oligodeoxynucleotide Can Protect against Yersinia pestis Infection

• Published in: Infection and Immunity Vol. 81; no. 6; pp. 2123 - 2132
• Main Authors: Hickey, Anthony J, Lin, Jr-Shiuan, Kummer, Lawrence W, Szaba, Frank M, Duso, Debra K, Tighe, Michael, Parent, Michelle A, Smiley, Stephen T
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.06.2013
• Subjects: Adjuvants, Immunologic - administration & dosage; Adjuvants, Immunologic - pharmacology; Administration, Intranasal; Animals; Antimicrobial agents; Gene Expression Regulation - immunology; Liver - microbiology; Lung - cytology; Lung - microbiology; Mice; Mice, Inbred C57BL; Microbial Immunity and Vaccines; Oligodeoxyribonucleotides - administration & dosage; Oligodeoxyribonucleotides - pharmacology; Plague - prevention & control; Specific Pathogen-Free Organisms; Toll-Like Receptor 9 - agonists; Toll-Like Receptor 9 - genetics; Toll-Like Receptor 9 - metabolism; Virulence; Yersinia pestis; Yersinia pestis - immunology; Yersinia pestis - pathogenicity
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.00316-13

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