Stool-Based Pathogen Detection Offers Advantages as an Outcome Measure for Water, Sanitation, and Hygiene Trials

• Published in: The American journal of tropical medicine and hygiene Vol. 102; no. 2; pp. 260 - 261
• Main Authors: Brown, Joe, Cumming, Oliver
• Format: Journal Article
• Language: English
• Published: United States Institute of Tropical Medicine 01.02.2020; The American Society of Tropical Medicine and Hygiene
• Subjects: Caregivers; Diarrhea; Feces - microbiology; Humans; Hygiene - standards; Outcome Assessment, Health Care; Pathogens; Pieces; Sanitation; Sanitation - standards; Water Quality - standards; Water Supply - standards

Most health impact trials of water, sanitation, and hygiene use caregiver-reported diarrhea in children as the primary outcome; this measure is known to be subject to considerable bias, especially when used in unblinded trials. Detection of enteric pathogens in stool or fecal waste via multiplex mol...