Role of original and modified Frey’s procedures in chronic pancreatitis

AIM To retrospectively review patients with chronic pancreatitis(CP) treated with Frey’s procedures between January 2009 and January 2014.METHODS A retrospective review was performed of patients with CP treated with Frey’s procedures between January 2009 and January 2014 in the Department of Pancrea...

Full description

Saved in:
Bibliographic Details
Published inWorld journal of gastroenterology : WJG Vol. 22; no. 47; pp. 10415 - 10423
Main Authors Tan, Chun-Lu, Zhang, Hao, Yang, Min, Li, Shao-Jun, Liu, Xu-Bao, Li, Ke-Zhou
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 21.12.2016
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:AIM To retrospectively review patients with chronic pancreatitis(CP) treated with Frey’s procedures between January 2009 and January 2014.METHODS A retrospective review was performed of patients with CP treated with Frey’s procedures between January 2009 and January 2014 in the Department of Pancreatic Surgery. A cross-sectional study of postoperative pain relief, quality of life(Qo L), and alcohol and nicotine abuse was performed by clinical interview, letters and telephone interview in January 2016. Qo L of patients was evaluated with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire(EORTC QLQ-C30) version 3.0. The patients were requested to fill in the questionnaires by themselves via correspondence or clinical interview.RESULTS A total of 80 patients were enrolled for analysis, including 44 who underwent the original Frey’s procedure and 36 who underwent a modified Frey’s procedure. The mean age was 46 years in the original group and 48 years in the modified group. Thirtyfive male patients(80%) were in the original group and 33(92%) in the modified group. There were no differences in the operating time, blood loss, and postoperative morbidity and mortality between the two groups. The mean follow-up was 50.3 mo in the original group and 48.7 mo in the modified group. There were no differences in endocrine and exocrine function preservation between the two groups. The original Frey’s procedure resulted in significantly betterpain relief, as shown by 5-year follow-up(P = 0.032), better emotional status(P = 0.047) and fewer fatigue symptoms(P = 0.028). When stratifying these patients by the M-ANNHEIM severity index, no impact was found on pain relief after the two types of surgery.CONCLUSION The original Frey’s procedure is as safe as the modified procedure, but the former yields better pain relief. The severity of CP does not affect postoperative pain relief.
Bibliography:Chun-Lu Tan;Hao Zhang;Min Yang;Shao-Jun Li;Xu-Bao Liu;Ke-Zhou Li;Department of Pancreatic Surgery, West China Hospital of Sichuan University
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Telephone: +86-28-85422474 Fax: +86-28-85422474
Correspondence to: Ke-Zhou Li, PhD, Department of Pancreatic Surgery, West China Hospital of Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China. huaxipancreas@163.com
Author contributions: Tan CL, Zhang H and Yang M contributed equally to this work; Tan CL, Zhang H and Li KZ designed the study; Tan CL, Yang M and Li SJ acquired the data; Tan CL, Zhang H and Yang M analyzed and interpreted the data; Tan CL, Zhang H, Yang M and Liu XB drafted the manuscript; Tan CL, Liu XB and Li KZ revised the manuscript.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v22.i47.10415