Effect of gastrectomy with bursectomy on prognosis of gastric cancer: A meta-analysis
AIM:To evaluate the effect of bursectomy on overall survival,recurrence-free survival and safety of patients with gastric cancer by performing a meta-analysis.METHODS:A literature search was performed in PubMed,EMBASE,and the Cochrane Library databases for clinical research that compared bursectomy...
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Published in | World journal of gastroenterology : WJG Vol. 20; no. 40; pp. 14986 - 14991 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
Baishideng Publishing Group Inc
28.10.2014
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Subjects | |
Online Access | Get full text |
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Summary: | AIM:To evaluate the effect of bursectomy on overall survival,recurrence-free survival and safety of patients with gastric cancer by performing a meta-analysis.METHODS:A literature search was performed in PubMed,EMBASE,and the Cochrane Library databases for clinical research that compared bursectomy with non-bursectomy published before October 2013.Inclusion and exclusion criteria were established and applied.Overall survival,recurrence-free survival,complications,hospital stay,operative time and blood loss were compared using hazard ratios(HRs),relative risks and weighted mean differences.Stata 12.0 software was used for statistical analysis.RESULTS:Four studies including 1130 patients were available for the analysis(430 in the bursectomy group,700 in the non-bursectomy group).No statistically significant difference was observed in the rate of com-plications between the bursectomy group and the nonbursectomy group.Bursectomy did not have a significant effect(combined HR=1.14,95%CI:0.88-1.47)on overall survival,and it was not a significant factor for recurrence-free survival(combined HR=1.06,95%CI:0.82-1.37).CONCLUSION:Gastrectomy with bursectomy is not superior to non-bursectomy in terms of survival.Bursectomy is not recommended as a routine procedure for the surgical treatment of gastric cancer. |
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Bibliography: | Wei-Song Shen;Hong-Qing Xi;Bo Wei;Lin Chen;Department of General Surgery, Chinese People’s Liberation Army General Hospital ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-3 content type line 23 Correspondence to: Lin Chen, MD, Professor, Department of General Surgery, Chinese People’s Liberation Army General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China. chenlinbj@163.com Author contributions: Shen WS and Xi HQ contributed equally to this work; Shen WS, Xi HQ, Wei B and Chen L designed the research; Shen WS and Chen L performed the research; Wei B and Chen L contributed analytical tools; Shen WS, Xi HQ and Wei B analyzed the data; Shen WS and Xi HQ wrote the paper. Telephone: +86-10-66938128 Fax: +86-10-68181689. |
ISSN: | 1007-9327 2219-2840 |
DOI: | 10.3748/wjg.v20.i40.14986 |