Action of Sodium Deoxycholate on Subcutaneous Human Tissue: Local and Systemic Effects

• Published in: Dermatologic surgery Vol. 33; no. 2; pp. 178 - 189
• Main Authors: YAGIMA ODO, MARINA EMIKO, CUCÉ, LUIZ CARLOS, ODO, LÍLIAN MAYUMI, NATRIELLI, ANDRÉA
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.02.2007; by the American Society for Dermatologic Surgery, Inc; Blackwell
• Subjects: Adipose Tissue - diagnostic imaging; Adipose Tissue - drug effects; Adult; Aged; Biological and medical sciences; Deoxycholic Acid - administration & dosage; Deoxycholic Acid - pharmacology; Dermatology; Detergents - administration & dosage; Detergents - pharmacology; Female; Humans; Injections, Subcutaneous; Medical sciences; Middle Aged; Skin plastic surgery; Subcutaneous Tissue - diagnostic imaging; Subcutaneous Tissue - drug effects; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surveys and Questionnaires; Treatment Outcome; Ultrasonography; Human; Treatment; Sodium; Dermatology; Surgery; Systemic; Disseminated; Subcutaneous tissue; Local effect

BACKGROUND Phosphatidylcholine injections have been used as a nonsurgical alternative to the surgical removal of undesired fat. Studies in cell culture suggest that sodium deoxycholate (SD) has a detergent action in fat reduction. OBJECTIVE The objective was to study SD in subcutaneous human tissue....