Therapeutic potentials and modulatory mechanisms of fatty acids in bone

• Published in: Cell proliferation Vol. 53; no. 2; pp. e12735 - n/a
• Main Authors: Bao, Minyue, Zhang, Kaiwen, Wei, Yangyini, Hua, Weihan, Gao, Yanzi, Li, Xin, Ye, Ling
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.02.2020; John Wiley and Sons Inc
• Subjects: Animals; Biomedical materials; Bone and Bones - metabolism; Bone diseases; Bone growth; bone homeostasis; Bone marrow; bone metabolism; Bone resorption; Bone turnover; Cartilage; Chemical compounds; Chemokines; Chondrocytes; Disease prevention; Disorders; Energy Metabolism - physiology; Fatty acids; Fatty Acids - metabolism; Fibroblasts; Fractures; Human subjects; Humans; Mesenchymal Stem Cells - metabolism; Mesenchyme; Metabolism; Metabolites; Neutrophils; Osteoblasts; Osteoblasts - metabolism; Osteoclasts; Osteoclasts - metabolism; Osteocytes; Osteogenesis; Osteogenesis - physiology; Osteoporosis; Pharmacology; Polyunsaturated fatty acids; Review; Reviews; Rheumatoid arthritis; Stem cells; Tumor necrosis factor-TNF; bone homeostasis; bone diseases; bone metabolism; fatty acids

Bone metabolism is a lifelong process that includes bone formation and resorption. Osteoblasts and osteoclasts are the predominant cell types associated with bone metabolism, which is facilitated by other cells such as bone marrow mesenchymal stem cells (BMMSCs), osteocytes and chondrocytes. As an i...