Patterns and trends in eczema management in UK primary care (2009–2018): A population‐based cohort study

• Published in: Clinical and experimental allergy Vol. 51; no. 3; pp. 483 - 494
• Main Authors: Lusignan, Simon, Alexander, Helen, Broderick, Conor, Dennis, John, McGovern, Andrew, Feeney, Clarie, Flohr, Carsten
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.03.2021; John Wiley and Sons Inc
• Subjects: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Age Factors; Anti-Infective Agents - therapeutic use; atopic dermatitis; atopic eczema; Child; Child, Preschool; Children; Cohort analysis; Corticosteroids; Dermatitis, Atopic - therapy; dermatology; Eczema; Emollients - therapeutic use; epidemiology; Ethnicity; Female; Glucocorticoids - therapeutic use; Healthcare Disparities - ethnology; Healthcare Disparities - statistics & numerical data; Histamine Antagonists - therapeutic use; Humans; Immunomodulating Agents - therapeutic use; Infant; Infants; Male; Middle Aged; Minority & ethnic groups; Original; ORIGINAL ARTICLES; Population studies; Population-based studies; Practice Patterns, Physicians' - statistics & numerical data; Primary care; Primary Health Care; Referral and Consultation - statistics & numerical data; Social Class; Socioeconomic factors; treatment; Trends; United Kingdom; Young Adult; United Kingdom; United Kingdom > UK; England; epidemiology; treatment; dermatology; eczema; atopic dermatitis; primary care; atopic eczema
• ISSN: 0954-7894; 1365-2222
• DOI: 10.1111/cea.13783

Background Despite the high disease burden of eczema, a contemporary overview of the patterns and trends in primary care healthcare utilization and treatment is lacking. Objective To quantify primary care consultations, specialist referrals, prescribing, and treatment escalation, in children and adults with eczema in England. Methods A large primary care research database was used to examine healthcare and treatment utilization in people with active eczema (n = 411,931). Management trends and variations by age, sex, socioeconomic status, and ethnicity were described from 2009 to 2018 inclusive. Results Primary care consultation rates increased from 87.8 (95% confidence interval [95% CI] 87.3–88.3) to 112.0 (95% CI 111.5–112.6) per 100 person‐years over 2009 to 2018. Specialist referral rates also increased from 3.8 (95% CI 3.7–3.9) to 5.0 (95% CI 4.9–5.1) per 100 person‐years over the same period. Consultation rates were highest in infants. Specialist referrals were greatest in the over 50s and lowest in people of lower socioeconomic status, despite a higher rate of primary care consultations. There were small changes in prescribing over time; emollients increased (prescribed to 48.5% of people with active eczema in 2009 compared to 51.4% in 2018) and topical corticosteroids decreased (57.3%–52.0%). Prescribing disparities were observed, including less prescribing of potent and very potent topical corticosteroids in non‐white ethnicities and people of lower socioeconomic status. Treatment escalation was more common with increasing age and in children of non‐white ethnicity. Conclusion and clinical relevance The management of eczema varies by sociodemographic status in England, with lower rates of specialist referral in people from more‐deprived backgrounds. There are different patterns of healthcare utilization, treatment, and treatment escalation in people of non‐white ethnicity and of more‐deprived backgrounds.