Targeting the ectopy‐triggering ganglionated plexuses without pulmonary vein isolation prevents atrial fibrillation

• Published in: Journal of cardiovascular electrophysiology Vol. 32; no. 2; pp. 235 - 244
• Main Authors: Sandler, Belinda, Kim, Min‐Young, Sikkel, Markus B., Malcolme‐Lawes, Louisa, Koa‐Wing, Michael, Whinnett, Zachary I., Coyle, Clare, Linton, Nick W. F., Lim, Phang B., Kanagaratnam, Prapa
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2021; John Wiley and Sons Inc
• Subjects: Ablation; Arrhythmia; atrial fibrillation; Atrial Fibrillation - diagnosis; Atrial Fibrillation - surgery; Atrium; autonomic nervous system; Cardiac arrhythmia; Catheter Ablation; Electrocardiography, Ambulatory; Fibrillation; ganglionated plexus; Heart Atria; Humans; Mapping; Original; Patients; pulmonary vein ectopy; Pulmonary Veins - diagnostic imaging; Pulmonary Veins - surgery; Recurrence; Tachycardia; Treatment Outcome; pulmonary vein ectopy; atrial fibrillation; catheter ablation; autonomic nervous system; ganglionated plexus

Background Ganglionated plexuses (GPs) are implicated in atrial fibrillation (AF). Endocardial high‐frequency stimulation (HFS) delivered within the local atrial refractory period can trigger ectopy and AF from specific GP sites (ET‐GP). The aim of this study was to understand the role of ET‐GP abla...