The roles of microRNAs played in lung diseases via regulating cell apoptosis

MicroRNAs (miRNAs) are a type of endogenous non-coding short-chain RNA, which plays a crucial role in the regulation of many essential cellular functions, including cellular migration, proliferation, invasion, autophagy, oxidative stress, apoptosis, and differentiation. The lung can be damaged by pa...

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Published inMolecular and cellular biochemistry Vol. 476; no. 12; pp. 4265 - 4275
Main Authors Huang, Qiaoling, Chen, Li, Bai, Qinqin, Tong, Ting, Zhou, You, Li, Zhongyu, Lu, Chunxue, Chen, Shenghua, Chen, Lili
Format Journal Article
LanguageEnglish
Published New York Springer US 01.12.2021
Springer
Springer Nature B.V
Subjects
Animals
Apoptosis
Apoptosis - physiology
Autophagy
Autophagy - physiology
Biochemistry
Biomedical and Life Sciences
Cardiology
Cell Movement - physiology
Cell Proliferation - physiology
Development and progression
Health aspects
Humans
Life Sciences
Lung diseases
Lung Diseases - genetics
Lung Diseases - metabolism
Lung Diseases - pathology
Medical Biochemistry
Microorganisms
MicroRNA
MicroRNAs
MicroRNAs - genetics
miRNA
Non-coding RNA
Oncology
Oxidative stress
Phagocytosis
Lung
MicroRNA
Apoptosis
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Summary:MicroRNAs (miRNAs) are a type of endogenous non-coding short-chain RNA, which plays a crucial role in the regulation of many essential cellular functions, including cellular migration, proliferation, invasion, autophagy, oxidative stress, apoptosis, and differentiation. The lung can be damaged by pathogenic microorganisms, as well as physical or chemical factors. Research has confirmed that miRNAs and lung cell apoptosis can affect the development and progression of several lung diseases. This article reviews the role of miRNAs in the development of lung disease through regulating host cell apoptosis.
ISSN:0300-8177
1573-4919
DOI:10.1007/s11010-021-04242-x