The Clinical Utility of Serum CXCR-2 Assessment in Colorectal Cancer (CRC) Patients

• Published in: Anticancer research Vol. 41; no. 3; pp. 1421 - 1428
• Main Authors: PĄCZEK, SARA, ŁUKASZEWICZ-ZAJĄC, MARTA, GRYKO, MARIUSZ, KULCZYŃSKA-PRZYBIK, AGNIESZKA, MROCZKO, BARBARA
• Format: Journal Article
• Language: English
• Published: Greece International Institute of Anticancer Research 01.03.2021
• Subjects: Angiogenesis; Biomarkers; Biomarkers, Tumor - blood; C-reactive protein; C-Reactive Protein - analysis; Cancer; Carcinoembryonic antigen; Carcinoembryonic Antigen - blood; Chemiluminescence; Chemokine receptors; Chemokines; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - blood; Colorectal Neoplasms - diagnosis; CXCR2 protein; Diagnosis; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoassay; Ligands; Lymphatic system; Male; Metastasis; Microparticles; Neutrophils; Prognosis; Proteins; Receptors, Interleukin-8B - blood; Regression analysis; ROC Curve; Serum levels; Statistical analysis; Tumor markers; Tumors; Poland; United States > US; colorectal cancer; CXCR-2; Chemokines; chemokine receptor

The current study aimed to evaluate the clinical utility of the levels of the C-X-C-motif chemokine receptor-2 (CXCR-2) serum receptor in comparison to the carcinoembryonic antigen (CEA) tumor marker and - the C-reactive protein (CRP) inflammatory marker in the diagnosis and prognosis of colorectal...