Loss of the Protease Dimerization Inhibition Activity of Tipranavir (TPV) and Its Association with the Acquisition of Resistance to TPV by HIV-1

• Published in: Journal of Virology Vol. 86; no. 24; pp. 13384 - 13396
• Main Authors: AOKI, Manabu, DANISH, Matthew L, AOKI-OGATA, Hiromi, AMANO, Masayuki, IDE, Kazuhiko, DAS, Debananda, KOH, Yasuhiro, MITSUYA, Hiroaki
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.12.2012
• Subjects: Amino Acid Sequence; Base Sequence; Biological and medical sciences; Cell Line; Dimerization; DNA Primers; Drug Resistance, Viral; Fundamental and applied biological sciences. Psychology; HIV Protease - chemistry; HIV Protease Inhibitors - pharmacology; Humans; Microbiology; Miscellaneous; Models, Molecular; Molecular Sequence Data; Polymerase Chain Reaction; Pyridines - pharmacology; Pyrones - pharmacology; Sequence Homology, Amino Acid; Vaccines and Antiviral Agents; Virology; Virus; Resistance; Tipranavir; HIV-1 virus; Retroviridae; Antiviral; Human immunodeficiency virus; Lentivirus
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.07234-11

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