Genetically determined resistance to 3-methylcholanthrene-induced lymphoma is expressed at the level of bone marrow-derived cells

Reciprocal bone marrow transfers were performed between mouse strains sensitive or resistant to 3-methylcholanthrene-induced thymic lymphoma. Sensitivity and resistance are properties inherent in bone marrow, and cannot be altered by maturation of marrow in an environment of the opposite phenotype.

Saved in:
Bibliographic Details
Published inThe Journal of experimental medicine Vol. 166; no. 2; pp. 565 - 570
Main Authors ISHIZAKA, S. T, LILLY, F
Format Journal Article
LanguageEnglish
Published New York, NY Rockefeller University Press 01.08.1987
The Rockefeller University Press
Subjects
Animals
Applied sciences
Bone Marrow Cells
Chimera
Drug Resistance
Exact sciences and technology
Lymphoma - chemically induced
Lymphoma - genetics
Methylcholanthrene
Mice
Mice, Inbred Strains
Other techniques and industries
Phenotype
Online AccessGet full text

Cover

More Information
Summary:Reciprocal bone marrow transfers were performed between mouse strains sensitive or resistant to 3-methylcholanthrene-induced thymic lymphoma. Sensitivity and resistance are properties inherent in bone marrow, and cannot be altered by maturation of marrow in an environment of the opposite phenotype.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0022-1007
1540-9538
DOI:10.1084/jem.166.2.565