Immune responses in diabetic nephropathy: Pathogenic mechanisms and therapeutic target

• Published in: Frontiers in immunology Vol. 13; p. 958790
• Main Authors: Chen, Jiahao, Liu, Qinhui, He, Jinhan, Li, Yanping
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 15.08.2022
• Subjects: diabetic nephropathy; immune responses; Immunology; inflammation; pathogenesis; therapeutic target

Diabetic nephropathy (DN) is a chronic, inflammatory disease affecting millions of diabetic patients worldwide. DN is associated with proteinuria and progressive slowing of glomerular filtration, which often leads to end-stage kidney diseases. Due to the complexity of this metabolic disorder and lac...