Glycoproteomic software solutions spotlight glycans

Software solutions pGlyco3 and StrucGP both aim to better assign the glycan part of a glycopeptide beyond simple glycosyl composition, but they differ in their strategies, their requirement for a glycan library and their applicability to O-glycopeptides.

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Bibliographic Details
Published inNature methods Vol. 18; no. 12; pp. 1457 - 1458
Main Author Khoo, Kay-Hooi
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.12.2021
Nature Publishing Group
Subjects
631/1647/296
631/45/221
Analysis
Bioinformatics
Biological Microscopy
Biological Techniques
Biomedical and Life Sciences
Biomedical Engineering/Biotechnology
Computer programs
Glycan
Glycopeptides
Glycoproteins
Glycosylation
Libraries
Life Sciences
Liquid chromatography
Localization
Mass spectrometry
News & Views
news-and-views
Peptides
Polysaccharides
Proteomics
Software
Taiwan
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Summary:Software solutions pGlyco3 and StrucGP both aim to better assign the glycan part of a glycopeptide beyond simple glycosyl composition, but they differ in their strategies, their requirement for a glycan library and their applicability to O-glycopeptides.
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ISSN:1548-7091
1548-7105
DOI:10.1038/s41592-021-01310-4