Dasatinib medication causing profound immunosuppression in a patient after haploidentical SCT: functional assays from whole blood as diagnostic clues

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Bibliographic Details
Published inBone marrow transplantation (Basingstoke) Vol. 48; no. 6; pp. 875 - 877
Main Authors WÖLFL, M, LANGHAMMER, F, WIEGERING, V, EYRICH, M, SCHLEGEL, P. G
Format Journal Article
LanguageEnglish
Published Basingstoke Nature Publishing Group 01.06.2013
Subjects
Allografts
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Bone marrow
Bone marrow, stem cells transplantation. Graft versus host reaction
Care and treatment
CD8-Positive T-Lymphocytes
Child
Dasatinib
DNA Virus Infections - blood
DNA Virus Infections - chemically induced
Health aspects
Hematopoietic stem cells
Humans
Immunologic Deficiency Syndromes - blood
Immunologic Deficiency Syndromes - chemically induced
Immunosuppression
Leukemia
Lymphocyte Count
Lymphocytosis - blood
Lymphocytosis - chemically induced
Male
Medical sciences
Precursor Cell Lymphoblastic Leukemia-Lymphoma - blood
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Protein Kinase Inhibitors - administration & dosage
Protein Kinase Inhibitors - adverse effects
Pyrimidines - administration & dosage
Pyrimidines - adverse effects
Risk factors
Stem Cell Transplantation
Thiazoles - administration & dosage
Thiazoles - adverse effects
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Transplantation
United States
Antineoplastic agent
Human
Whole blood
Dasatinib
Chemotherapy
Immunosuppression
Haploidentical graft
Treatment
Hematology
Tyrosine kinase inhibitor
Multikinase inhibitor
Diagnosis
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More Information
ISSN:0268-3369
1476-5365
DOI:10.1038/bmt.2012.246