KSHV Reprogramming of Host Energy Metabolism for Pathogenesis

• Published in: Frontiers in cellular and infection microbiology Vol. 11; p. 621156
• Main Authors: Liu, Xiaoqing, Zhu, Caixia, Wang, Yuyan, Wei, Fang, Cai, Qiliang
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 12.05.2021
• Subjects: Cellular and Infection Microbiology; energy metabolism; herpesvirus; KSHV; oncogenesis; viral reprogramming

Reprogramming of energy metabolism is a key for cancer development. Kaposi’s sarcoma-associated herpesvirus (KSHV), a human oncogenic herpesvirus, is tightly associated with several human malignancies by infecting B-lymphocyte or endothelial cells. Cancer cell energy metabolism is mainly dominated b...