Effect of rye bran on excretion of bile acids, cholesterol, nitrogen, and fat in human subjects with ileostomies

• Published in: The American journal of clinical nutrition Vol. 59; no. 2; pp. 389 - 394
• Main Authors: Zhang, JX, Lundin, E, Hallmans, G, Adlercreutz, H, Andersson, H, Bosaeus, I, Åman, P, Stenling, R, Dahlgren, S
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 01.02.1994; American Society for Clinical Nutrition; American Society for Clinical Nutrition, Inc
• Subjects: ACIDE BILIAIRE; ACIDOS BILIARES; Adult; Aged; analysis; AZOTE; Bile; bile acids; Bile Acids and Salts; Bile Acids and Salts - analysis; Bile Acids and Salts - metabolism; Biological and medical sciences; blood; blood lipids; blood serum; bran; Bread; CENTENO; CHOLESTEROL; Cholesterol - blood; Cholesterol - metabolism; COLESTEROL; CORPS GRAS; Diet; Dietary Fiber; Energy Metabolism; EXCRECION; EXCRETION; Female; FEMME; GRASAS; Humans; Ileostomy; Ileum; Ileum - metabolism; INTESTIN; INTESTINOS; LIPEMIA; LIPEMIE; Lipid Metabolism; Lipids; Lipids - blood; Male; Medical research; Medical sciences; metabolism; Middle Aged; MUJERES; Nitrogen; Nitrogen - blood; Nitrogen - metabolism; NITROGENO; Oils & fats; OPERACIONES QUIRURGICAS; OPERATION CHIRURGICALE; rye; Rye bran; SALVADO; Secale; SEIGLE; serum lipids; SERUM SANGUIN; SON; Stomach, duodenum, intestine, rectum, anus; SUERO SANGUINEO; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; women; cholesterol; Rye bran; serum lipids; bile acids; humans; ileostomy; Human; Ileostomy; Diet therapy; Bile acid; Surgery; Lipids; Supplemented diet; Nitrogen; Dietary fiber; Cholesterol; Rye
• ISSN: 0002-9165; 1938-3207
• DOI: 10.1093/ajcn/59.2.389

The excretion of bile acids, cholesterol, dry matter, nitrogen, fat, and energy in ileostomy effluent, and plasma lipid concentrations were studied in eight subjects with ileostomies. The subjects consumed a wheat bread-based, low-fiber diet (LFD) for 3 wk and a rye bran bread-based, high-fiber diet (HFD) for 3 wk. The ileal excretion of dry matter, nitrogen, fat, and energy was higher during the HFD period. The daily excretion and the percentage of conjugated bile acids were significantly higher and the percentage of free bile acids lower in the ileostomy effluents during the HFD as compared with the LFD period. No significant difference in the excretion of cholesterol, net cholesterol, sterol, or net sterol was noted between the HFD and LFD periods. No significant differences in plasma concentrations of HDL-, LDL-, and total cholesterol, and apolipoprotein A-I and B were observed between the two 3-wk dietary periods.