Thermotropic liquid crystal films for biosensors and beyond
We briefly review studies of liquid crystal films suspended in submillimeter size grids for biosensing applications and beyond. Due to intense recent research, the sensitivity of liquid crystal films to targeted biologically relevant agents can be increased, and the LC surface can be functionalized...
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| Published in | Journal of materials chemistry. B, Materials for biology and medicine Vol. 5; no. 26; pp. 561 - 578 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
14.07.2017
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| Online Access | Get full text |
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| Summary: | We briefly review studies of liquid crystal films suspended in submillimeter size grids for biosensing applications and beyond. Due to intense recent research, the sensitivity of liquid crystal films to targeted biologically relevant agents can be increased, and the LC surface can be functionalized to be sensitive only to pre-assigned pathogens. Beyond sensor applications, we show that novel liquid crystal defect structures can be used to manipulate separation and deposition of lipids. Finally, we demonstrate that not only the nematic liquid crystal phase, but also chiral nematic (cholesteric and blue phase) and smectic liquid crystals can be used for sensing and may extend the sensitivity and/or the selection of biomaterials, which can be sensed.
Recent results on structural properties and possible bio-sensing applications of planar liquid crystal films are reviewed. |
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| Bibliography: | Dr Piotr Popov received his BS degree in Physics and Materials Science from Ivanovo State University, Russia in 2010 under the guidance of Prof. Usol'tseva Nadezhda Vasilyevna and completed his PhD work in Physics at Kent State University in 2015 under the guidance of Prof. Elizabeth Mann and Prof. Antal Jákli. Dr Popov currently works as an R&D Scientist at RavenWindow, Inc in Denver, Colorado. He is involved in the design and development of thermochromic smart-windows using liquid crystal technology. Dr Antal Jákli has obtained PhD in Physics from Eötvös University in Budapest in 1986 and his DSc from the Hungarian Academy of Sciences in 2000. Currently he is Professor of Chemical Physics at the Liquid Crystal Institute of Kent State University in Kent, OH, USA. His research focuses on the physical properties of liquid crystals and soft matter with special emphasis on biological aspects, piezoelectricity and ferroelectricity. He has co-authored a textbook "One and two dimensional fluids", written over 250 peer-reviewed papers, 10 book chapters, and holds 17 US patents. He is an associate Editor of Physical Review E. Dr Elizabeth Mann is Professor of Physics at Kent State University, which she joined in 1998. She received her BS degree in physics from Case Western Reserve University and completed her PhD work in soft matter physics at the Ecole Normal Supérieure in Paris (PhD Paris VI.). She did post-doctoral work in France (the Institut Charles Sadron and INSERM, in Strasbourg) and in Switzerland (Federal Institute of Technology-Zurich), bridging laboratories of macromolecular science, odontology, and environmental engineering. Her research interests center on lipid, liquid crystalline, and (bio)macromolecular films at interfaces. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 2050-750X 2050-7518 |
| DOI: | 10.1039/c7tb00809k |