A new diketopiperazine from the gorgonian coral Menella kanisa

Chemical investigation on the gorgonian Menella kanisa collected from Beibu Gulf led to the isolation of a new diketopiperazine, named menazepine A (1), as well as three known diketopiperazines, namely cyclo(4-hydroxyprolylleucyl) (2), cyclo(Pro-Leu) (3) and cyclo(4-hydroxyprolylphenylalanyl) (4). T...

Full description

Saved in:
Bibliographic Details
Published inNatural product research Vol. 28; no. 7; pp. 473 - 476
Main Authors Gao, Chenghai, Lin, Lin, Long, Bin, Chen, Yinning, He, Bijuan, Sun, Haiyan, Huang, Riming
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 03.04.2014
Subjects
Animals
Anthozoa - chemistry
Artemia - drug effects
brine shrimp lethality
Decapoda
diketopiperazine
Diketopiperazines - chemistry
Diketopiperazines - isolation & purification
Diketopiperazines - pharmacology
Dipeptides - isolation & purification
Gorgonacea
menazepine A
Menella kanisa
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Peptides, Cyclic - isolation & purification
Online AccessGet full text

Cover

More Information
Summary:Chemical investigation on the gorgonian Menella kanisa collected from Beibu Gulf led to the isolation of a new diketopiperazine, named menazepine A (1), as well as three known diketopiperazines, namely cyclo(4-hydroxyprolylleucyl) (2), cyclo(Pro-Leu) (3) and cyclo(4-hydroxyprolylphenylalanyl) (4). The structure of the new diketopiperazine was elucidated on the basis of extensive spectroscopic analysis and by comparing the data with those of related metabolites. Compounds 1-4 were also evaluated for brine shrimp lethality.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2013.879134