Antibiotic susceptibility patterns of Neisseria meningitidis isolates from patients and asymptomatic carriers

The activities of seven antimicrobial agents used for treatment and prophylaxis of meningococcal disease was investigated against 901 Neisseria meningitidis isolates, 112 of which were recovered from patients and 789 of which were recovered from asymptomatic carriers. The proportions of isolates wit...

Full description

Saved in:
Bibliographic Details
Published inAntimicrobial agents and chemotherapy Vol. 44; no. 6; pp. 1705 - 1707
Main Authors Arreaza, L, de La Fuente, L, Vázquez, J A
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.06.2000
SeriesNote
Subjects
Ampicillin - pharmacology
Ampicillin - therapeutic use
Carrier State
Humans
Meningococcal Infections - drug therapy
Meningococcal Infections - metabolism
Neisseria meningitidis
Neisseria meningitidis - drug effects
Penicillin Resistance
Penicillins - pharmacology
Penicillins - therapeutic use
Susceptibility
Online AccessGet full text

Cover

More Information
Summary:The activities of seven antimicrobial agents used for treatment and prophylaxis of meningococcal disease was investigated against 901 Neisseria meningitidis isolates, 112 of which were recovered from patients and 789 of which were recovered from asymptomatic carriers. The proportions of isolates with decreased susceptibility to penicillin were 55.3 and 39.0%, respectively. Penicillin- and ampicillin-intermediate strains were more common among serogroup C meningococci than among non-serogroup C meningococci from both patients and carriers.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
Corresponding author. Mailing address: Servicio de Bacteriología, Laboratorio de Referencia de Meningococos, Centro Nacional de Microbiología, Instituto de Salud Carlos III. 28220 Majadahonda, Madrid, Spain. Phone: 34-1-5097901. Fax: 34-1-5097966. E-mail: jvazquez@isciii.es.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.44.6.1705-1707.2000