OMMR: Co-registration toolbox of OPM-MEG and MRI

• Published in: Frontiers in neuroscience Vol. 16; p. 984036
• Main Authors: Cao, Fuzhi, An, Nan, Xu, Weinan, Wang, Wenli, Li, Wen, Wang, Chunhui, Yang, Yanfei, Xiang, Min, Gao, Yang, Ning, Xiaolin
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 15.09.2022
• Subjects: co-registration; electromagnetic digitization system; magnetoencephalography (MEG); Neuroscience; OPM-MEG; optical scanner
• ISSN: 1662-453X; 1662-4548; 1662-453X
• DOI: 10.3389/fnins.2022.984036

Magnetoencephalography (MEG) based on optically pumped magnetometers (OPM-MEG) has shown better flexibility in sensor configuration compared with the conventional superconducting quantum interference devices-based MEG system while being better suited for all-age groups. However, this flexibility presents challenges for the co-registration of MEG and magnetic resonance imaging (MRI), hindering adoption. This study presents a toolbox called OMMR, developed in Matlab, that facilitates the co-registration step for researchers and clinicians. OMMR integrates the co-registration methods of using the electromagnetic digitization system and two types of optical scanners (the structural-light and laser scanner). As the first open-source co-registration toolbox specifically for OPM-MEG, the toolbox aims to standardize the co-registration process and set the ground for future applications of OPM-MEG.