Comparative Distribution, Correlation, and Chemometric Analyses of Selected Metals in Scalp Hair of Angina Patients and Healthy Subjects

Numerous epidemiological studies are preponderance of evidences intimating development of coronary artery disease caused by metal imbalance. The present study was aimed to analyze Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Na, Pb, Sr, and Zn in the scalp hair of angina patients and healthy subjects/controls emp...

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Bibliographic Details
Published inBiological trace element research Vol. 168; no. 1; pp. 33 - 43
Main Authors Ilyas, Asim, Ahmad, Hamad, Shah, Munir H.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.11.2015
Springer Nature B.V
Subjects
Adult
Aged
Angina pectoris
Angina Pectoris - epidemiology
Angina Pectoris - metabolism
Atomic absorption spectrophotometry
Biochemistry
Biomedical and Life Sciences
Biotechnology
Cadmium
Cardiovascular disease
Diet
Female
Hair
Hair - chemistry
Hair analysis
Humans
Lead
Life Sciences
Male
Metals - analysis
Metals - metabolism
Middle Aged
Multivariate analysis
Nutrition
Oncology
Pakistan - epidemiology
Rural Population
Sex Characteristics
Spectral analysis
Spectrophotometry
Spectrophotometry, Atomic
Tobacco Use - epidemiology
Trace elements
Trace Elements - analysis
Trace metals
Urban Population
Pakistan
Scalp hair
AAS
Angina
Multivariate analysis
Trace metals
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Summary:Numerous epidemiological studies are preponderance of evidences intimating development of coronary artery disease caused by metal imbalance. The present study was aimed to analyze Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Na, Pb, Sr, and Zn in the scalp hair of angina patients and healthy subjects/controls employing HNO 3 –HCLO 4 -based wet digestion followed by quantification with atomic absorption spectrophotometry. The average concentrations of Cd, Cu, Cr, Fe, Mn, Pb, and Sr revealed significantly higher levels in scalp hair of patients than controls; however, Na and Zn were appreciably higher in healthy subjects. Dissimilarity in the trace metal distribution was also observed with gender, residence, dietary habits, and smoking habits of both donor groups. The correlation study and multivariate analyses revealed diverse mutual relationships and apportionment of the trace metals in the scalp hair of patients and controls.
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ISSN:0163-4984
1559-0720
DOI:10.1007/s12011-015-0350-3