Elevated body mass in National Football League players linked to cognitive impairment and decreased prefrontal cortex and temporal pole activity

Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of bod...

Full description

Saved in:
Bibliographic Details
Published inTranslational psychiatry Vol. 2; no. 1; p. e68
Main Authors Willeumier, K, Taylor, D V, Amen, D G
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.01.2012
Nature Publishing Group
Subjects
631/378/1457/1945
692/699/2743/393
692/699/476
692/700/1421/1846/2771
Adult
Aged
Behavioral Sciences
Biological Psychology
Body Height
Body Mass Index
Brain Concussion - physiopathology
Brain Injury, Chronic - physiopathology
Cognition Disorders - physiopathology
Football
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Multimodal Imaging
Neurosciences
Obesity - physiopathology
Original
original-article
Overweight - physiopathology
Pharmacotherapy
Positron-Emission Tomography
Prefrontal Cortex - blood supply
Psychiatry
Regional Blood Flow - physiology
Temporal Lobe - blood supply
Tomography, X-Ray Computed
Waist Circumference
waist-to-height ratio (WHtR)
cognition
single photon computed tomography (SPECT)
prefrontal cortex
temporal pole
body mass index (BMI)
Online AccessGet full text
ISSN2158-3188
2158-3188
DOI10.1038/tp.2011.67

Cover

Abstract Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of body mass as measured by waist-to-height ratio (WHtR) on regional cerebral blood flow using single-photon emission computed tomography imaging in 38 healthy weight (WHtR mean 49.34±2.8; age 58±9.6) and 38 overweight (WHtR mean 58.7±4.7; age 58±13.3) retired National Football League football players. After matching for age and position, we used a two sample t -test to determine the differences in blood flow in healthy versus overweight subjects. Statistical parametric mapping revealed a higher WHtR ratio is associated with decreased blood flow in Brodmann areas 8, 9 and 10, brain regions involved in attention, reasoning and executive function ( P <0.05, family-wise error) along with deficits in the temporal pole. Moreover, overweight athletes had significant decrease in attention ( P =0.01326), general cognitive proficiency ( P =0.012; Microcog: Assessment of Cognitive Functioning) and memory ( P =0.005; Mild Cognitive Impairment Screen). The association between elevated WHtR percentage and decreased blood flow in the prefrontal cortex and temporal pole may be correlated with the decreased performance on tests of attention and memory. These findings suggest that a weight management program may be critical to the health of athletes who have been exposed to mild brain trauma during their careers.
AbstractList Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of body mass as measured by waist-to-height ratio (WHtR) on regional cerebral blood flow using single-photon emission computed tomography imaging in 38 healthy weight (WHtR mean 49.34±2.8; age 58±9.6) and 38 overweight (WHtR mean 58.7±4.7; age 58±13.3) retired National Football League football players. After matching for age and position, we used a two sample t-test to determine the differences in blood flow in healthy versus overweight subjects. Statistical parametric mapping revealed a higher WHtR ratio is associated with decreased blood flow in Brodmann areas 8, 9 and 10, brain regions involved in attention, reasoning and executive function (P<0.05, family-wise error) along with deficits in the temporal pole. Moreover, overweight athletes had significant decrease in attention (P=0.01326), general cognitive proficiency (P=0.012; Microcog: Assessment of Cognitive Functioning) and memory (P=0.005; Mild Cognitive Impairment Screen). The association between elevated WHtR percentage and decreased blood flow in the prefrontal cortex and temporal pole may be correlated with the decreased performance on tests of attention and memory. These findings suggest that a weight management program may be critical to the health of athletes who have been exposed to mild brain trauma during their careers.
Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of body mass as measured by waist-to-height ratio (WHtR) on regional cerebral blood flow using single-photon emission computed tomography imaging in 38 healthy weight (WHtR mean 49.34±2.8; age 58±9.6) and 38 overweight (WHtR mean 58.7±4.7; age 58±13.3) retired National Football League football players. After matching for age and position, we used a two sample t -test to determine the differences in blood flow in healthy versus overweight subjects. Statistical parametric mapping revealed a higher WHtR ratio is associated with decreased blood flow in Brodmann areas 8, 9 and 10, brain regions involved in attention, reasoning and executive function ( P <0.05, family-wise error) along with deficits in the temporal pole. Moreover, overweight athletes had significant decrease in attention ( P =0.01326), general cognitive proficiency ( P =0.012; Microcog: Assessment of Cognitive Functioning) and memory ( P =0.005; Mild Cognitive Impairment Screen). The association between elevated WHtR percentage and decreased blood flow in the prefrontal cortex and temporal pole may be correlated with the decreased performance on tests of attention and memory. These findings suggest that a weight management program may be critical to the health of athletes who have been exposed to mild brain trauma during their careers.
Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of body mass as measured by waist-to-height ratio (WHtR) on regional cerebral blood flow using single-photon emission computed tomography imaging in 38 healthy weight (WHtR mean 49.34 ± 2.8; age 58 ± 9.6) and 38 overweight (WHtR mean 58.7 ± 4.7; age 58 ± 13.3) retired National Football League football players. After matching for age and position, we used a two sample t-test to determine the differences in blood flow in healthy versus overweight subjects. Statistical parametric mapping revealed a higher WHtR ratio is associated with decreased blood flow in Brodmann areas 8, 9 and 10, brain regions involved in attention, reasoning and executive function (P<0.05, family-wise error) along with deficits in the temporal pole. Moreover, overweight athletes had significant decrease in attention (P = 0.01326), general cognitive proficiency (P = 0.012; Microcog: Assessment of Cognitive Functioning) and memory (P=0.005; Mild Cognitive Impairment Screen). The association between elevated WHtR percentage and decreased blood flow in the prefrontal cortex and temporal pole may be correlated with the decreased performance on tests of attention and memory. These findings suggest that a weight management program may be critical to the health of athletes who have been exposed to mild brain trauma during their careers.
Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of body mass as measured by waist-to-height ratio (WHtR) on regional cerebral blood flow using single-photon emission computed tomography imaging in 38 healthy weight (WHtR mean 49.34 ± 2.8; age 58 ± 9.6) and 38 overweight (WHtR mean 58.7 ± 4.7; age 58 ± 13.3) retired National Football League football players. After matching for age and position, we used a two sample t-test to determine the differences in blood flow in healthy versus overweight subjects. Statistical parametric mapping revealed a higher WHtR ratio is associated with decreased blood flow in Brodmann areas 8, 9 and 10, brain regions involved in attention, reasoning and executive function (P<0.05, family-wise error) along with deficits in the temporal pole. Moreover, overweight athletes had significant decrease in attention (P = 0.01326), general cognitive proficiency (P = 0.012; Microcog: Assessment of Cognitive Functioning) and memory (P=0.005; Mild Cognitive Impairment Screen). The association between elevated WHtR percentage and decreased blood flow in the prefrontal cortex and temporal pole may be correlated with the decreased performance on tests of attention and memory. These findings suggest that a weight management program may be critical to the health of athletes who have been exposed to mild brain trauma during their careers.Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in sports, which expose them to repetitive concussions, may be at heightened risk for cognitive impairment. Here, we investigated the effects of body mass as measured by waist-to-height ratio (WHtR) on regional cerebral blood flow using single-photon emission computed tomography imaging in 38 healthy weight (WHtR mean 49.34 ± 2.8; age 58 ± 9.6) and 38 overweight (WHtR mean 58.7 ± 4.7; age 58 ± 13.3) retired National Football League football players. After matching for age and position, we used a two sample t-test to determine the differences in blood flow in healthy versus overweight subjects. Statistical parametric mapping revealed a higher WHtR ratio is associated with decreased blood flow in Brodmann areas 8, 9 and 10, brain regions involved in attention, reasoning and executive function (P<0.05, family-wise error) along with deficits in the temporal pole. Moreover, overweight athletes had significant decrease in attention (P = 0.01326), general cognitive proficiency (P = 0.012; Microcog: Assessment of Cognitive Functioning) and memory (P=0.005; Mild Cognitive Impairment Screen). The association between elevated WHtR percentage and decreased blood flow in the prefrontal cortex and temporal pole may be correlated with the decreased performance on tests of attention and memory. These findings suggest that a weight management program may be critical to the health of athletes who have been exposed to mild brain trauma during their careers.
Author Willeumier, K
Amen, D G
Taylor, D V
Author_xml – sequence: 1
  givenname: K
  surname: Willeumier
  fullname: Willeumier, K
  organization: Amen Clinics
– sequence: 2
  givenname: D V
  surname: Taylor
  fullname: Taylor, D V
  organization: Amen Clinics
– sequence: 3
  givenname: D G
  surname: Amen
  fullname: Amen, D G
  email: docamen@amenclinic.com
  organization: Amen Clinics
BackLink https://www.ncbi.nlm.nih.gov/pubmed/22832730$$D View this record in MEDLINE/PubMed
BookMark eNptktFuFCEUhiemxtbaGx_AkHhjanaFYWZgb5qYplWTjd7oNWHgzEplYAR2476Fj9yz3dasVUKAwHf-8-ccnldHIQaoqpeMzhnl8l2Z5jVlbN6JJ9VJzVo540zKo4PzcXWW8w3F0TaSCfasOq5ryWvB6Un1-8rDRhewpI92S0adM3GBfNbFxaA9uY6x9Np7sgS9WgOZvN5CysS78AODSiQmroIrbgPEjZN2aYRQiA6WWDAJdEZqSjCkGArqmZgK_Lp7LzBOMeHdFD0QbVDDle2L6umgfYaz-_20-nZ99fXy42z55cOny_fLmWmausxq2vR112pLTdPTwfLe6MEMbBhk10hbt5RZzYaecSEbAYL1dtBCDJR3hvcc-Gl1sded1v0I1qBr9KKm5Eadtipqp_5-Ce67WsWN4pwuWr5AgTf3Ain-XEMuanTZgPc6QFxnhd2hVOLSIfr6EXoT1wnLi5RYsAYn2wm-OnT0x8pDsxCge8CkmDPWVBlX7hqFBp3HjLukUpVJ7b6E6gSGnD8KeVD9L_x2D2eEwgrSgc1_6Vs3gMjv
CitedBy_id crossref_primary_10_1089_neu_2020_7484
crossref_primary_10_4103_mohe_mohe_26_21
crossref_primary_10_1007_s13311_021_01028_3
crossref_primary_10_1007_s12603_023_1894_2
crossref_primary_10_1080_02640414_2014_926382
crossref_primary_10_3233_JAD_200655
crossref_primary_10_1002_oby_23187
crossref_primary_10_1016_j_nicl_2023_103538
crossref_primary_10_3389_fpsyt_2023_1224914
crossref_primary_10_1080_13803395_2016_1139057
crossref_primary_10_1186_2193_1801_1_2
crossref_primary_10_1016_j_ijchp_2024_100483
crossref_primary_10_1155_2013_435629
crossref_primary_10_3389_fnhum_2018_00514
crossref_primary_10_1093_cercor_bhx008
crossref_primary_10_1093_braincomms_fcae147
crossref_primary_10_1007_s11695_020_05065_3
crossref_primary_10_1136_bjsports_2020_103400
crossref_primary_10_1080_1028415X_2024_2339729
crossref_primary_10_1016_j_biopsych_2012_12_020
crossref_primary_10_4085_1062_6050_297_18
crossref_primary_10_1016_j_biopsych_2015_11_023
crossref_primary_10_1016_j_csm_2020_08_012
crossref_primary_10_1136_jnnp_2019_321170
crossref_primary_10_1016_j_pnpbp_2024_111132
crossref_primary_10_1111_cns_12776
crossref_primary_10_1186_s12974_016_0641_4
crossref_primary_10_1249_JSR_0000000000001028
crossref_primary_10_1371_journal_pone_0207874
crossref_primary_10_1007_s11695_024_07475_z
crossref_primary_10_1016_j_neubiorev_2019_05_012
crossref_primary_10_1001_jamanetworkopen_2022_9478
crossref_primary_10_1097_HTR_0000000000000420
crossref_primary_10_1016_j_neubiorev_2013_07_009
crossref_primary_10_1055_s_0040_1713633
Cites_doi 10.1038/oby.2011.16
10.1001/jama.297.4.363
10.1038/oby.2008.469
10.1002/hbm.460020402
10.1002/hbm.20916
10.1097/PAF.0b013e3181ca7f35
10.1001/jama.2009.716
10.1080/02791072.2011.566489
10.1519/JSC.0b013e31815f5d97
10.1111/j.1467-789X.2010.00825.x
10.1227/NEU.0b013e318212bc7b
10.1016/j.comppsych.2006.05.001
10.1080/02699050701426931
10.1002/(SICI)1097-0193(1999)7:4<254::AID-HBM4>3.0.CO;2-G
10.1146/annurev.neuro.24.1.167
10.1111/j.1939-3938.2009.01064.x
10.1038/35036228
10.1016/j.acn.2008.03.003
10.1002/ana.21377
10.1016/j.jpeds.2007.03.044
10.1227/01.NEU.0000175725.75780.DD
10.1176/appi.neuropsych.23.1.98
10.3200/JACH.57.1.33-38
10.3233/JAD-2007-11309
10.1002/hbm.20870
ContentType Journal Article
Copyright The Author(s) 2012
Copyright Nature Publishing Group Jan 2012
Copyright © 2012 Macmillan Publishers Limited 2012 Macmillan Publishers Limited
Copyright_xml – notice: The Author(s) 2012
– notice: Copyright Nature Publishing Group Jan 2012
– notice: Copyright © 2012 Macmillan Publishers Limited 2012 Macmillan Publishers Limited
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
7X8
5PM
DOI 10.1038/tp.2011.67
DatabaseName Springer Nature OA Free Journals
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni Edition)
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
ProQuest One Community College
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Health & Medical Collection (Alumni Edition)
Medical Database
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList Publicly Available Content Database

MEDLINE

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: C6C
  name: Springer Nature OA Free Journals
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
DocumentTitleAlternate NFL players body mass impairs brain function
EISSN 2158-3188
EndPage e68
ExternalDocumentID PMC3309539
4068969101
22832730
10_1038_tp_2011_67
Genre Journal Article
GroupedDBID ---
0R~
3V.
4.4
53G
5VS
7X7
88E
8FI
8FJ
AAJSJ
AAKDD
ABUWG
ACGFO
ACGFS
ACMJI
ACSMW
ADBBV
ADFRT
AENEX
AFKRA
AHMBA
AJTQC
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AMTXH
AOIJS
BAPOH
BAWUL
BCNDV
BENPR
BPHCQ
BVXVI
C6C
CCPQU
DIK
EBLON
EBS
EJD
EMOBN
FYUFA
GROUPED_DOAJ
GX1
HMCUK
HYE
KQ8
LGEZI
LOTEE
M1P
M~E
NADUK
NAO
NXXTH
OK1
PIMPY
PQQKQ
PROAC
PSQYO
RNS
RNT
RNTTT
RPM
SNYQT
UKHRP
AASML
AAYXX
CITATION
PHGZM
PHGZT
CGR
CUY
CVF
ECM
EIF
NPM
7XB
8FK
AARCD
AZQEC
DWQXO
K9.
PJZUB
PKEHL
PPXIY
PQEST
PQUKI
PRINS
7X8
PUEGO
5PM
ID FETCH-LOGICAL-c442t-204b265ad0c4b0fd3bcafcf1ff8648d2501da1fb137847e71bdfa77f036c3b3e3
IEDL.DBID C6C
ISSN 2158-3188
IngestDate Thu Aug 21 18:21:05 EDT 2025
Fri Sep 05 11:19:45 EDT 2025
Wed Aug 13 04:08:50 EDT 2025
Thu Apr 03 06:55:48 EDT 2025
Thu Apr 24 23:04:48 EDT 2025
Tue Jul 01 00:54:58 EDT 2025
Fri Feb 21 02:39:08 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords waist-to-height ratio (WHtR)
cognition
single photon computed tomography (SPECT)
prefrontal cortex
temporal pole
body mass index (BMI)
Language English
License This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c442t-204b265ad0c4b0fd3bcafcf1ff8648d2501da1fb137847e71bdfa77f036c3b3e3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
OpenAccessLink https://www.nature.com/articles/tp.2011.67
PMID 22832730
PQID 1791491419
PQPubID 2041978
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_3309539
proquest_miscellaneous_1030080306
proquest_journals_1791491419
pubmed_primary_22832730
crossref_citationtrail_10_1038_tp_2011_67
crossref_primary_10_1038_tp_2011_67
springer_journals_10_1038_tp_2011_67
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2012-01-01
PublicationDateYYYYMMDD 2012-01-01
PublicationDate_xml – month: 01
  year: 2012
  text: 2012-01-01
  day: 01
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: United States
PublicationTitle Translational psychiatry
PublicationTitleAbbrev Transl Psychiatry
PublicationTitleAlternate Transl Psychiatry
PublicationYear 2012
Publisher Nature Publishing Group UK
Nature Publishing Group
Publisher_xml – name: Nature Publishing Group UK
– name: Nature Publishing Group
References Walther, Birdsill, Glisky, Ryan (CR13) 2010; 31
Gazdzinski, Kornak, Weiner, Meyerhoff (CR26) 2008; 63
Gunstad, Paul, Cohen, Tate, Spitznagel, Gordon (CR4) 2007; 48
Volkow, Wang, Telang, Fowler, Goldstein, Alia-Klein (CR14) 2009; 17
Ashburner, Friston (CR12) 1999; 7
Anstey, Cherbuin, Budge, Young (CR23) 2011; 12
Mathews, Wagner (CR5) 2008; 57
Boeka, Lokken (CR25) 2008; 23
Kaiser, Womack, Green, Pollard, Miller, Crouse (CR2) 2008; 22
Omalu, Bailes, Hamilton, Kamboh, Hammers, Case (CR19) 2011; 69
Tucker, Vogel, Lincoln, Dunn, Ahrensfield, Allen (CR27) 2009; 301
De Beaumont, Brisson, Lassonde, Jolicoeur (CR22) 2007; 21
Amen, Newberg, Thatcher, Jin, Wu, Keator (CR7) 2011; 23
Guskiewicz, Marshall, Bailes, McCrea, Cantu, Randolph (CR18) 2005; 57
Amen, Wu, Taylor, Willeumier (CR6) 2011; 43
Willeumier, Taylor, Amen (CR8) 2011; 19
Friston, Holmes, Worsley, Poline, Frith, Frackowiak (CR11) 1995; 2
Raji, Ho, Parikshak, Becker, Lopez, Kuller (CR24) 2010; 31
CR9
Laurson, Eisenmann (CR15) 2007; 297
Miller, Cohen (CR17) 2001; 24
Harp, Hecht (CR3) 2005; 293
Trenkle, Shankle, Azen (CR10) 2007; 11
Omalu, Bailes, Hammers, Fitzsimmons (CR20) 2010; 31
Miller (CR16) 2000; 1
Malina, Morano, Barron, Miller, Cumming, Kontos (CR1) 2007; 151
Omalu, Hamilton, Kamboh, DeKosky, Bailes (CR21) 2010; 6
KM Guskiewicz (BFtp201167_CR18) 2005; 57
J Ashburner (BFtp201167_CR12) 1999; 7
K Walther (BFtp201167_CR13) 2010; 31
BI Omalu (BFtp201167_CR21) 2010; 6
ND Volkow (BFtp201167_CR14) 2009; 17
KC Willeumier (BFtp201167_CR8) 2011; 19
EK Miller (BFtp201167_CR16) 2000; 1
DG Amen (BFtp201167_CR6) 2011; 43
RM Malina (BFtp201167_CR1) 2007; 151
S Gazdzinski (BFtp201167_CR26) 2008; 63
L De Beaumont (BFtp201167_CR22) 2007; 21
BI Omalu (BFtp201167_CR20) 2010; 31
JB Harp (BFtp201167_CR3) 2005; 293
CA Raji (BFtp201167_CR24) 2010; 31
GE Kaiser (BFtp201167_CR2) 2008; 22
DL Trenkle (BFtp201167_CR10) 2007; 11
EM Mathews (BFtp201167_CR5) 2008; 57
KJ Friston (BFtp201167_CR11) 1995; 2
AG Boeka (BFtp201167_CR25) 2008; 23
B Omalu (BFtp201167_CR19) 2011; 69
DG Amen (BFtp201167_CR7) 2011; 23
BFtp201167_CR9
AM Tucker (BFtp201167_CR27) 2009; 301
KR Laurson (BFtp201167_CR15) 2007; 297
J Gunstad (BFtp201167_CR4) 2007; 48
KJ Anstey (BFtp201167_CR23) 2011; 12
EK Miller (BFtp201167_CR17) 2001; 24
16239884 - Neurosurgery. 2005 Oct;57(4):719-26; discussion 719-26
10408769 - Hum Brain Mapp. 1999;7(4):254-66
17577714 - Brain Inj. 2007 Jun;21(6):631-44
19662657 - Hum Brain Mapp. 2010 Mar;31(3):353-64
21311507 - Obesity (Silver Spring). 2011 May;19(5):1095-7
17889073 - J Pediatr. 2007 Oct;151(4):378-82
19998366 - Hum Brain Mapp. 2010 Jul;31(7):1052-64
11283309 - Annu Rev Neurosci. 2001;24:167-202
18948965 - Obesity (Silver Spring). 2009 Jan;17(1):60-5
15741527 - JAMA. 2005 Mar 2;293(9):1061-2
18448310 - Arch Clin Neuropsychol. 2008 Jul;23(4):467-74
18682343 - J Am Coll Health. 2008 Jul-Aug;57(1):33-8
21615001 - J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5
18409192 - Ann Neurol. 2008 May;63(5):652-7
11252769 - Nat Rev Neurosci. 2000 Oct;1(1):59-65
17145283 - Compr Psychiatry. 2007 Jan-Feb;48(1):57-61
18296982 - J Strength Cond Res. 2008 Jan;22(1):243-9
17851183 - J Alzheimers Dis. 2007 Jun;11(3):323-35
21348917 - Obes Rev. 2011 May;12(5):e426-37
21304145 - J Neuropsychiatry Clin Neurosci. 2011 Winter;23(1):98-106
20032774 - Am J Forensic Med Pathol. 2010 Jun;31(2):130-2
21358359 - Neurosurgery. 2011 Jul;69(1):173-83; discussion 183
20201914 - J Forensic Nurs. 2010 Spring;6(1):40-6
19470988 - JAMA. 2009 May 27;301(20):2111-9
17244832 - JAMA. 2007 Jan 24;297(4):363-4
References_xml – volume: 19
  start-page: 1095
  year: 2011
  end-page: 1097
  ident: CR8
  article-title: Elevated BMI is associated with decreased blood flow in the prefrontal cortex using SPECT imaging in healthy adults
  publication-title: Obesity (Silver Spring)
  doi: 10.1038/oby.2011.16
– volume: 297
  start-page: 363
  year: 2007
  end-page: 364
  ident: CR15
  article-title: Prevalence of overweight among high school football linemen
  publication-title: JAMA
  doi: 10.1001/jama.297.4.363
– volume: 17
  start-page: 60
  year: 2009
  end-page: 65
  ident: CR14
  article-title: Inverse association between BMI and prefrontal metabolic activity in healthy adults
  publication-title: Obesity (Silver Spring)
  doi: 10.1038/oby.2008.469
– volume: 2
  start-page: 189
  year: 1995
  end-page: 210
  ident: CR11
  article-title: Statistical parametric maps in functional imaging: a general linear approach
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.460020402
– volume: 31
  start-page: 1052
  year: 2010
  end-page: 1064
  ident: CR13
  article-title: Structural brain differences and cognitive functioning related to body mass index in older females
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.20916
– volume: 31
  start-page: 130
  year: 2010
  end-page: 132
  ident: CR20
  article-title: Chronic traumatic encephalopathy, suicides and parasuicides in professional American athletes: the role of the forensic pathologist
  publication-title: Am J Forensic Med Pathol
  doi: 10.1097/PAF.0b013e3181ca7f35
– volume: 293
  start-page: 1061
  year: 2005
  end-page: 1062
  ident: CR3
  article-title: Obesity in the National Football League
  publication-title: JAMA
– volume: 301
  start-page: 2111
  year: 2009
  end-page: 2119
  ident: CR27
  article-title: Prevalence of cardiovascular disease risk factors among National Football League players
  publication-title: JAMA
  doi: 10.1001/jama.2009.716
– volume: 31
  start-page: 353
  year: 2010
  end-page: 364
  ident: CR24
  article-title: Brain structure and obesity
  publication-title: Hum Brain Mapp
– volume: 43
  start-page: 1
  year: 2011
  end-page: 5
  ident: CR6
  article-title: Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation
  publication-title: J Psychoactive Drugs
  doi: 10.1080/02791072.2011.566489
– volume: 22
  start-page: 243
  year: 2008
  end-page: 249
  ident: CR2
  article-title: Morphological profiles for first-year National Collegiate Athletic Association Division I football players
  publication-title: J Strength Cond Res
  doi: 10.1519/JSC.0b013e31815f5d97
– volume: 12
  start-page: e426
  year: 2011
  end-page: e437
  ident: CR23
  article-title: Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies
  publication-title: Obes Rev
  doi: 10.1111/j.1467-789X.2010.00825.x
– volume: 69
  start-page: 173
  year: 2011
  end-page: 183
  ident: CR19
  article-title: Emerging histomorphologic phenotypes of chronic traumatic encephalopathy [CTE] in American athletes
  publication-title: Neurosurgery
  doi: 10.1227/NEU.0b013e318212bc7b
– volume: 48
  start-page: 57
  year: 2007
  end-page: 61
  ident: CR4
  article-title: Elevated body mass index is associated with executive dysfunction in otherwise healthy adults
  publication-title: Compr Psychiatry
  doi: 10.1016/j.comppsych.2006.05.001
– volume: 21
  start-page: 631
  year: 2007
  end-page: 644
  ident: CR22
  article-title: Long-term electrophysiological changes in athletes with a history of multiple concussions
  publication-title: Brain Inj
  doi: 10.1080/02699050701426931
– volume: 7
  start-page: 254
  year: 1999
  end-page: 266
  ident: CR12
  article-title: Nonlinear spatial normalization using basis functions
  publication-title: Hum Brain Mapp
  doi: 10.1002/(SICI)1097-0193(1999)7:4<254::AID-HBM4>3.0.CO;2-G
– volume: 24
  start-page: 167
  year: 2001
  end-page: 202
  ident: CR17
  article-title: An integrative theory of prefrontal cortex function
  publication-title: Annu Rev Neurosci
  doi: 10.1146/annurev.neuro.24.1.167
– volume: 6
  start-page: 40
  year: 2010
  end-page: 46
  ident: CR21
  article-title: Chronic traumatic encephalopathy (CTE) in a National Football League Player: case report and emerging medicolegal practice questions
  publication-title: J Forensic Nurs
  doi: 10.1111/j.1939-3938.2009.01064.x
– volume: 1
  start-page: 59
  year: 2000
  end-page: 65
  ident: CR16
  article-title: The prefrontal cortex and cognitive control
  publication-title: Nat Rev Neurosci
  doi: 10.1038/35036228
– volume: 23
  start-page: 467
  year: 2008
  end-page: 474
  ident: CR25
  article-title: Neuropsychological performance of a clinical sample of extremely obese individuals
  publication-title: Arch Clin Neuropsychol
  doi: 10.1016/j.acn.2008.03.003
– volume: 63
  start-page: 652
  year: 2008
  end-page: 657
  ident: CR26
  article-title: Body mass index and magnetic resonance markers of brain integrity in adults
  publication-title: Ann Neurol
  doi: 10.1002/ana.21377
– volume: 151
  start-page: 378
  year: 2007
  end-page: 382
  ident: CR1
  article-title: Overweight and obesity among youth participants in American football
  publication-title: J Pediatr
  doi: 10.1016/j.jpeds.2007.03.044
– ident: CR9
– volume: 57
  start-page: 719
  year: 2005
  end-page: 726
  ident: CR18
  article-title: Association between recurrent concussion and late-life cognitive impairment in retired professional football players
  publication-title: Neurosurgery
  doi: 10.1227/01.NEU.0000175725.75780.DD
– volume: 23
  start-page: 98
  year: 2011
  end-page: 106
  ident: CR7
  article-title: Impact of playing American professional football on long-term brain function
  publication-title: J Neuropsychiatry Clin Neurosci
  doi: 10.1176/appi.neuropsych.23.1.98
– volume: 57
  start-page: 33
  year: 2008
  end-page: 38
  ident: CR5
  article-title: Prevalence of overweight and obesity in collegiate American football players, by position
  publication-title: J Am Coll Health
  doi: 10.3200/JACH.57.1.33-38
– volume: 11
  start-page: 323
  year: 2007
  end-page: 335
  ident: CR10
  article-title: Detecting cognitive impairment in primary care: performance assessment of three screening instruments
  publication-title: J Alzheimers Dis
  doi: 10.3233/JAD-2007-11309
– volume: 17
  start-page: 60
  year: 2009
  ident: BFtp201167_CR14
  publication-title: Obesity (Silver Spring)
  doi: 10.1038/oby.2008.469
– volume: 151
  start-page: 378
  year: 2007
  ident: BFtp201167_CR1
  publication-title: J Pediatr
  doi: 10.1016/j.jpeds.2007.03.044
– volume: 31
  start-page: 1052
  year: 2010
  ident: BFtp201167_CR13
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.20916
– volume: 43
  start-page: 1
  year: 2011
  ident: BFtp201167_CR6
  publication-title: J Psychoactive Drugs
  doi: 10.1080/02791072.2011.566489
– volume: 23
  start-page: 98
  year: 2011
  ident: BFtp201167_CR7
  publication-title: J Neuropsychiatry Clin Neurosci
  doi: 10.1176/appi.neuropsych.23.1.98
– volume: 6
  start-page: 40
  year: 2010
  ident: BFtp201167_CR21
  publication-title: J Forensic Nurs
  doi: 10.1111/j.1939-3938.2009.01064.x
– volume: 48
  start-page: 57
  year: 2007
  ident: BFtp201167_CR4
  publication-title: Compr Psychiatry
  doi: 10.1016/j.comppsych.2006.05.001
– volume: 12
  start-page: e426
  year: 2011
  ident: BFtp201167_CR23
  publication-title: Obes Rev
  doi: 10.1111/j.1467-789X.2010.00825.x
– volume: 297
  start-page: 363
  year: 2007
  ident: BFtp201167_CR15
  publication-title: JAMA
  doi: 10.1001/jama.297.4.363
– volume: 57
  start-page: 33
  year: 2008
  ident: BFtp201167_CR5
  publication-title: J Am Coll Health
  doi: 10.3200/JACH.57.1.33-38
– volume: 22
  start-page: 243
  year: 2008
  ident: BFtp201167_CR2
  publication-title: J Strength Cond Res
  doi: 10.1519/JSC.0b013e31815f5d97
– volume: 7
  start-page: 254
  year: 1999
  ident: BFtp201167_CR12
  publication-title: Hum Brain Mapp
  doi: 10.1002/(SICI)1097-0193(1999)7:4<254::AID-HBM4>3.0.CO;2-G
– volume: 21
  start-page: 631
  year: 2007
  ident: BFtp201167_CR22
  publication-title: Brain Inj
  doi: 10.1080/02699050701426931
– volume: 23
  start-page: 467
  year: 2008
  ident: BFtp201167_CR25
  publication-title: Arch Clin Neuropsychol
  doi: 10.1016/j.acn.2008.03.003
– volume: 57
  start-page: 719
  year: 2005
  ident: BFtp201167_CR18
  publication-title: Neurosurgery
  doi: 10.1227/01.NEU.0000175725.75780.DD
– volume: 63
  start-page: 652
  year: 2008
  ident: BFtp201167_CR26
  publication-title: Ann Neurol
  doi: 10.1002/ana.21377
– volume: 293
  start-page: 1061
  year: 2005
  ident: BFtp201167_CR3
  publication-title: JAMA
– volume: 1
  start-page: 59
  year: 2000
  ident: BFtp201167_CR16
  publication-title: Nat Rev Neurosci
  doi: 10.1038/35036228
– volume: 69
  start-page: 173
  year: 2011
  ident: BFtp201167_CR19
  publication-title: Neurosurgery
  doi: 10.1227/NEU.0b013e318212bc7b
– volume: 31
  start-page: 353
  year: 2010
  ident: BFtp201167_CR24
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.20870
– volume: 301
  start-page: 2111
  year: 2009
  ident: BFtp201167_CR27
  publication-title: JAMA
  doi: 10.1001/jama.2009.716
– volume: 2
  start-page: 189
  year: 1995
  ident: BFtp201167_CR11
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.460020402
– ident: BFtp201167_CR9
– volume: 19
  start-page: 1095
  year: 2011
  ident: BFtp201167_CR8
  publication-title: Obesity (Silver Spring)
  doi: 10.1038/oby.2011.16
– volume: 24
  start-page: 167
  year: 2001
  ident: BFtp201167_CR17
  publication-title: Annu Rev Neurosci
  doi: 10.1146/annurev.neuro.24.1.167
– volume: 31
  start-page: 130
  year: 2010
  ident: BFtp201167_CR20
  publication-title: Am J Forensic Med Pathol
  doi: 10.1097/PAF.0b013e3181ca7f35
– volume: 11
  start-page: 323
  year: 2007
  ident: BFtp201167_CR10
  publication-title: J Alzheimers Dis
  doi: 10.3233/JAD-2007-11309
– reference: 21348917 - Obes Rev. 2011 May;12(5):e426-37
– reference: 17145283 - Compr Psychiatry. 2007 Jan-Feb;48(1):57-61
– reference: 17577714 - Brain Inj. 2007 Jun;21(6):631-44
– reference: 17244832 - JAMA. 2007 Jan 24;297(4):363-4
– reference: 21615001 - J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5
– reference: 18682343 - J Am Coll Health. 2008 Jul-Aug;57(1):33-8
– reference: 10408769 - Hum Brain Mapp. 1999;7(4):254-66
– reference: 11283309 - Annu Rev Neurosci. 2001;24:167-202
– reference: 18409192 - Ann Neurol. 2008 May;63(5):652-7
– reference: 15741527 - JAMA. 2005 Mar 2;293(9):1061-2
– reference: 19998366 - Hum Brain Mapp. 2010 Jul;31(7):1052-64
– reference: 21304145 - J Neuropsychiatry Clin Neurosci. 2011 Winter;23(1):98-106
– reference: 18448310 - Arch Clin Neuropsychol. 2008 Jul;23(4):467-74
– reference: 19662657 - Hum Brain Mapp. 2010 Mar;31(3):353-64
– reference: 17851183 - J Alzheimers Dis. 2007 Jun;11(3):323-35
– reference: 19470988 - JAMA. 2009 May 27;301(20):2111-9
– reference: 11252769 - Nat Rev Neurosci. 2000 Oct;1(1):59-65
– reference: 16239884 - Neurosurgery. 2005 Oct;57(4):719-26; discussion 719-26
– reference: 20032774 - Am J Forensic Med Pathol. 2010 Jun;31(2):130-2
– reference: 20201914 - J Forensic Nurs. 2010 Spring;6(1):40-6
– reference: 21311507 - Obesity (Silver Spring). 2011 May;19(5):1095-7
– reference: 18948965 - Obesity (Silver Spring). 2009 Jan;17(1):60-5
– reference: 18296982 - J Strength Cond Res. 2008 Jan;22(1):243-9
– reference: 21358359 - Neurosurgery. 2011 Jul;69(1):173-83; discussion 183
– reference: 17889073 - J Pediatr. 2007 Oct;151(4):378-82
SSID ssj0000548171
Score 2.1052096
Snippet Obesity is a risk factor for neurodegenerative disease and has been shown to adversely affect cognitive function. Professional athletes who participate in...
SourceID pubmedcentral
proquest
pubmed
crossref
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage e68
SubjectTerms 631/378/1457/1945
692/699/2743/393
692/699/476
692/700/1421/1846/2771
Adult
Aged
Behavioral Sciences
Biological Psychology
Body Height
Body Mass Index
Brain Concussion - physiopathology
Brain Injury, Chronic - physiopathology
Cognition Disorders - physiopathology
Football
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Multimodal Imaging
Neurosciences
Obesity - physiopathology
Original
original-article
Overweight - physiopathology
Pharmacotherapy
Positron-Emission Tomography
Prefrontal Cortex - blood supply
Psychiatry
Regional Blood Flow - physiology
Temporal Lobe - blood supply
Tomography, X-Ray Computed
Waist Circumference
SummonAdditionalLinks – databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELZgKyEuqLxDCzKiFw5R49hJvKcK0K4qRCuEqNRb5CesFJLQzVblX_CTO5M4oWURUm6eOE7G9nyZGX9DyAFYJJslOo8lU3kstIJ9UCQq9tarOXcsVQkeFD45zY_PxMfz7Dw43NYhrXLcE_uN2jYGfeSHSKMp4GLzo_ZnjFWjMLoaSmjcJTuwBctsRnbeL04_f5m8LABIJCvYyEvK5WHXDrydfWH5G5ZoC15uZ0n-FSrtLdBylzwI0JG-G3T9kNxx9SNy7yQExx-T34vKXQJ0tFQ39hf9AbCYrmoamK8rumyaTquqop-c-rZxtK0U4m2KMVy4qWvolEtE8fDk6gI9h1TVltoeXK5BqoX3QM4D6M9gnu5V3x4IriraNpWjeFYCS1I8IWfLxdcPx3EouBAbIdIOVozQaZ4pmxihE2-5Nsobz7yXuZAW0BKzinnNeAFGzRVMg0aLwoMVNFxzx5-SWd3U7jmhNtcsmVvpXcaFBQTPrcnyYp5YU3iXyoi8HT9-aQIbORbFqMo-Ks5l2bUlKqrMi4i8mWTbgYPjn1L7ow7LsA7X5Z9ZE5HXUzOsIAyLqNo1mzX2g7gZ_p0i8mxQ-fQYJAcCgJdEpLg1GSYBZOe-3VKvvvcs3ZwjlR8892CcNjeGtTX6F_8f_R65D4Lp4PvZJ7PuYuNeAhrq9Ksw5a8BC_4QJg
  priority: 102
  providerName: ProQuest
Title Elevated body mass in National Football League players linked to cognitive impairment and decreased prefrontal cortex and temporal pole activity
URI https://link.springer.com/article/10.1038/tp.2011.67
https://www.ncbi.nlm.nih.gov/pubmed/22832730
https://www.proquest.com/docview/1791491419
https://www.proquest.com/docview/1030080306
https://pubmed.ncbi.nlm.nih.gov/PMC3309539
Volume 2
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1bi9QwFA7uLogv4t3qOkTcFx-KTZMmncdxmGEZ3EXUhXkrSZPoQG3LTkd2_4U_2XN6Y8fxQSi0kJNLm8v5es7JF0LOQCPZJDIyTJmWoTAa1kER6dBbr6fcsVhHuFH44lKeX4nVOln3NDnbPqyyo7Rsl-khOuxDU3d0m1IdkROkbEee_Lmcj_YUgB4pU2xgIOXpnSz7OucASB7GQ_7lFG11zfIRediDRDrrmvWY3HPlE3L_oneDPyW_F4X7BSDRUlPZW_oTADDdlLTnuC7osqoao4uCfnL6-87RutCIrCl6ayFTU9ExaojiNsnNNdoIqS4ttS2M3IJUDe-B7AZQXo4RuTdtek9lVdC6KhzFXRF4-MQzcrVcfJufh_3RCmEuRNzA3BAmlom2US5M5C03ufa5Z96nUqQWcBGzmnnDuAL15RQz0HdKedB3OTfc8efkuKxK95JQKw2Lpjb1LuHCAlbnNk-kmkY2V97FaUDeDx8_y3vecTz-osha_zdPs6bOsKMyqQLybpStO7aNf0qdDn2Y9TNumyHNqoCLTQPydkyGuYIOEF26arfFchAhw19SQF50XT5WgzRAAOWigKi9wTAKIA_3fkq5-dHycXOOpH1Q79kwbO4066D1r_5P7DV5AE9xZ-05JcfN9c69AfzTmAk5Ums1ISez2errCu4fF5efv0za6TBpbQp_AHHcDog
linkProvider Springer Nature
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELZKK0EviDeBAkaUA4eocey8Dgjx2NWW7q4QaqXegh3bdKWQhG4W6L_gl_AbmcmLlkXcKuXmR5zMePx5xv6GkF1YkXTgqdCNmQxdoSTYQeFJ12orE26YLz28KDybh5Mj8f44ON4gv_q7MHissreJjaHWZYY-8j2k0RTwsORV9dXFrFEYXe1TaLRqcWDOvsOWbfly_x3I97nvj0eHbydul1XAzYTwa1ALofwwkNrLhPKs5iqTNrPM2jgUsQZIwLRkVjEegeU2EVMw7CiyYOozrrjh0O8VsgUwI4FZtPVmNP_wcfDqAACKWcR6HlQe79VVyxPaJLI_t_Ktwdn1U5l_hWabFW98g1zvoCp93erWTbJhilvk6qwLxt8mP0e5-QZQVVNV6jP6BWA4XRS0Y9rO6bgsayXznE6N_LwytMol4nuKMWNoVJd0OLtE8bLm4hQ9lVQWmuoGzC6hVgXfgRwL0F-G54J_NOUdoVZOqzI3FO9mYAqMO-ToUkRxl2wWZWHuE6pDxbxEx9YEXGjYMXCdBWGUeDqLrPFjh7zof36adeznmIQjT5soPI_TukpRUGkYOeTZULdqOT_-WWunl2Hazftl-kdLHfJ0KIYZi2EYWZhytcR-EKfDXs0h91qRD69BMiIAlJ5DogvKMFRANvCLJcXipGEF5xypA-G9u73anBvW2ugf_H_0T8i1yeFsmk735wcPyTY08lu_0w7ZrE9X5hEgsVo97tSfkk-XPeN-A4I5ToM
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3NbtQwEB6VrVRxQfw3UMCIcuAQbRxnk-wBIaC7amm7qhCVegt2bMNKIQndLNC34Hn6dJ3JHy2LuFXKzY5jZ8bjz57xNwDbuCLpkadCN-YydAMl0Q4GnnSttnIsDPelRxeFD2fh7nHw4WR0sgbn3V0YCqvsbGJtqHWR0hn5kGg0A3z4eGjbsIijnemb8rtLGaTI09ql02hUZN-c_cTt2-L13g7K-qXvTyef3u-6bYYBNw0Cv0IVCZQfjqT20kB5VguVSptabm0cBrFGeMC15FZxEaEVNxFXOIQosmj2U6GEEdjuDViPcFWMB7D-bjI7-tif8CAYinnEO05UEQ-rsuEMrZPaX1oFV6DtaoTmX27aevWb3oZbLWxlbxs9uwNrJr8LG4etY_4e_J5k5gfCVs1Uoc_YN4TkbJ6zlnU7Y9OiqJTMMnZg5JelYWUmCesz8h_jS1XB-jgmRhc356d0aslkrpmuge0Ca5U4DuJbwPZSihH-VZe35FoZK4vMMLqnQekw7sPxtYjiAQzyIjebwHSouDfWsTUjEWjcPQidjsJo7Ok0ssaPHXjV_fwkbZnQKSFHltQeeREnVZmQoJIwcuBFX7ds-D_-WWurk2HS2oBF8kdjHXjeF-PsJZeMzE2xXFA7hNlx3-bAw0bk_WeImAjBpedAdEUZ-grEDH61JJ9_rRnChSAaQfzudqc2l7q10vtH_-_9M9jAmZYc7M32H8NNfMdvjqC2YFCdLs0TBGWVetpqP4PP1z3hLgCCa1Kv
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Elevated+body+mass+in+National+Football+League+players+linked+to+cognitive+impairment+and+decreased+prefrontal+cortex+and+temporal+pole+activity&rft.jtitle=Translational+psychiatry&rft.au=Willeumier%2C+K&rft.au=Taylor%2C+D+V&rft.au=Amen%2C+D+G&rft.date=2012-01-01&rft.pub=Nature+Publishing+Group&rft.eissn=2158-3188&rft.volume=2&rft.issue=1&rft.spage=e68&rft_id=info:doi/10.1038%2Ftp.2011.67&rft_id=info%3Apmid%2F22832730&rft.externalDocID=PMC3309539
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2158-3188&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2158-3188&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2158-3188&client=summon