Standardization of clinical protocols in oral malodor research

• Published in: Journal of breath research Vol. 6; no. 1; pp. 17101 - 17110
• Main Authors: Yaegaki, Ken, Brunette, Donald M, Tangerman, Albert, Choe, Yong-Sahm, Winkel, Edwin G, Ito, Sayaka, Kitano, Tomohiro, Ii, Hisataka, Calenic, Bogdan, Ishkitiev, Nikolay, Imai, Toshio
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 01.03.2012
• Subjects: Biomedical Research - standards; Breath Tests - methods; Chromatography, Gas; Clinical Protocols - standards; guideline; halitosis; Halitosis - diagnosis; Humans; Mouth; Oral Hygiene; oral malodor; research design; Sulfur Compounds - analysis; volatile sulfur compounds

The objective of this study is to standardize protocols for clinical research into oral malodor caused by volatile sulfur compounds (VSCs). To detect VSCs, a gas chromatograph (GC) using a flame photometric detector equipped with a bandpass filter (at 393 nm) is the gold standard (sensitivity: 5 × 1...