Thought for food: Clinical evidence for the dietary prevention strategy in cardiovascular disease

A modified diet has been advocated for the past 50 years for prevention of cardiovascular disease. The evidence has in the past been largely epidemiological and experimental, with relatively limited support from clinical trials. However a major element of this strategy, reduction in intake of satura...

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Bibliographic Details
Published inInternational journal of evidence-based healthcare Vol. 11; no. 4; p. 330
Main Authors Lewis, Barry, Sullivan, David R, Watts, Gerald F
Format Journal Article
LanguageEnglish
Published Australia 01.12.2013
Subjects
Atherosclerosis - physiopathology
Cardiovascular Diseases - ethnology
Cardiovascular Diseases - physiopathology
Cardiovascular Diseases - prevention & control
Cholesterol - blood
Cholesterol - metabolism
Cholesterol, LDL - metabolism
Continental Population Groups - ethnology
Diet
Diet, Mediterranean
Dietary Fats - metabolism
Humans
cardiovascular disease
Mediterranean diet
low-density lipoprotein cholesterol
prevention
dietary recommendation
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Summary:A modified diet has been advocated for the past 50 years for prevention of cardiovascular disease. The evidence has in the past been largely epidemiological and experimental, with relatively limited support from clinical trials. However a major element of this strategy, reduction in intake of saturated fats, has recently been called into question; the evidence for and against this view is critically reviewed. A Cochrane review, and recent trials, have advanced our understanding of the role of diet and of optimal dietary recommendation strategy. Here we consider these advances in the light of established knowledge.
ISSN:1744-1609
DOI:10.1111/1744-1609.12047