Polysomnographic evidence of sleep apnoea disorders in lean and overweight haemodialysis patients

• Published in: Journal of renal care Vol. 33; no. 4; p. 159
• Main Authors: Sakkas, Giorgos K, Karatzaferi, Christina, Liakopoulos, Vassilios, Maridaki, Maria D, Lavdas, Eleftherios, Giannaki, Christoforos D, Gourgoulianis, Konstantinos I, Stefanidis, Ioannis
• Format: Journal Article
• Language: English
• Published: United States 01.10.2007
• Subjects: Absorptiometry, Photon; Aged; Attitude to Health; Body Composition; Body Mass Index; Case-Control Studies; Causality; Cross-Sectional Studies; Female; Humans; Intra-Abdominal Fat - diagnostic imaging; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - therapy; Male; Middle Aged; Nursing Methodology Research; Overweight - classification; Overweight - complications; Overweight - diagnosis; Polysomnography - methods; Quality of Life - psychology; Renal Dialysis; Severity of Illness Index; Sleep Apnea Syndromes - diagnosis; Sleep Apnea Syndromes - etiology; Sleep Apnea Syndromes - psychology; Statistics, Nonparametric; Surveys and Questionnaires; Tomography, X-Ray Computed
• ISSN: 1755-6678; 1755-6686
• DOI: 10.1111/j.1755-6686.2007.tb00066.x

Sleep apnoea disorders affect a large proportion of patients with renal failure. However, it is unknown whether body composition and visceral adiposity predispose haemodialysis patients to sleep apnoea disorders. Forty-one dialysis patients were divided in two groups according to the BMI score as; the Lean group (N=21, 1F/20M, BMI = 21.3 +/- 2.1) and the Overweight group (N=20, 9F/11M, BMI = 28.3 +/- 2.8). Sleep disturbances assessed by a full polysomnography (PSG), visceral adipose tissue (VAT), calculated by computed tomography, the quality of life, assessed by the SF-36, and the body composition, measured by DEXA. None of the PSG parameters were different between the two groups. Only visceral adiposity was correlated significantly with sleep apnoea disorders. BMI and percent of total body fat do not seem to predispose for sleep apnoea disorders. Rather it is the increased fat deposition in abdominal area that plays the pivotal role.