Assessing Propofol Induction of Anesthesia Dose Using Bispectral Index Analysis

In this study we sought to determine the propofol requirement and hemodynamic effects as guided by bispectral index (BIS) analysis during induction of anesthesia. Sixty patients were enrolled in this study. Propofol, 2 mg/kg, was given to Group I for induction. Propofol was administered for inductio...

Full description

Saved in:
Bibliographic Details
Published inAnesthesia and analgesia Vol. 98; no. 1; pp. 128 - 131
Main Authors Gürses, Ercan, Sungurtekin, Hülya, Tomatir, Erkan, Dogan, Hakan
Format Journal Article
LanguageEnglish
Published Hagerstown, MD International Anesthesia Research Society 01.01.2004
Lippincott
Subjects
Adult
Anesthesia
Anesthesia, General
Anesthesia, Intravenous
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anesthetics, Intravenous - administration & dosage
Biological and medical sciences
Dose-Response Relationship, Drug
Electroencephalography - drug effects
Female
Hemodynamics - drug effects
Humans
Male
Medical sciences
Middle Aged
Monitoring, Intraoperative
Propofol
Anesthesia
Propofol
General anesthetic
Induction
Online AccessGet full text

Cover

More Information
Summary:In this study we sought to determine the propofol requirement and hemodynamic effects as guided by bispectral index (BIS) analysis during induction of anesthesia. Sixty patients were enrolled in this study. Propofol, 2 mg/kg, was given to Group I for induction. Propofol was administered for induction until loss of response to verbal commands and until BIS values were around 50 to Groups II and III. After induction, the smallest BIS value was different in Group I. Decreases in total propofol dose were 36% and 43% in Groups II and III respectively as compared with Group I. The dose of propofol assessed by BIS analysis results in an important reduction of propofol requirement without side effects.
ISSN:0003-2999
1526-7598
DOI:10.1213/01.ANE.0000090314.43496.1D