Chlamydia trachomatis proctitis masquerading as carcinoma rectum: First case report from India

While proctitis is caused both by infectious and noninfectious causes, infectious causes are acquired typically sexually. Chlamydia trachomatis, which is the most frequent bacterial pathogen causing sexually transmitted infections worldwide, is one of the causative agents of proctitis. We report a c...

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Published inIndian journal of pathology & microbiology Vol. 60; no. 2; pp. 259 - 261
Main Authors Dhawan, Benu, Makharia, Govind Kumar, Juyal, Deepak, Sebastian, Sujeesh, Bhatia, Riti, Khanna, Neena
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.04.2017
Wolters Kluwer Medknow Publications
Subjects
Adult
Biopsy
Bisexual
Carcinoma - pathology
Chlamydia
Chlamydia Infections - diagnosis
Chlamydia Infections - pathology
Chlamydia trachomatis
Chlamydia trachomatis - isolation & purification
Colonoscopy
Diagnosis, Differential
Health aspects
hematochezia
Histocytochemistry
Humans
India
inflammatory bowel disease
lymphogranuloma venereum
Male
Microscopy
Polymerase Chain Reaction
proctitis
Proctitis - diagnosis
Proctitis - pathology
Rectal Neoplasms - pathology
Rectum
Rectum - pathology
Risk factors
Sexual and Gender Minorities
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Summary:While proctitis is caused both by infectious and noninfectious causes, infectious causes are acquired typically sexually. Chlamydia trachomatis, which is the most frequent bacterial pathogen causing sexually transmitted infections worldwide, is one of the causative agents of proctitis. We report a case history of a bisexual male who presented to us with rectal bleeding. The colonoscopy showed a nodular ulcerated lesion in the rectum suggestive of rectal malignancy, but biopsies from rectal mass did not reveal malignancy. A rectal biopsy was positive for C. trachomatis by polymerase chain reaction assay, and a diagnosis of C. trachomatis proctitis was made. Considering the invasive anorectal disease and patient's sexual history, he was treated with prolonged doxycycline therapy as per Centres for Disease Control and Prevention's treatment recommendation for lymphogranuloma venereum. A high index of clinical suspicion along with appropriate microbiological testing can clinch the diagnosis of C. trachomatis infection.
ISSN:0377-4929
0974-5130
DOI:10.4103/IJPM.IJPM_114_16