Hypersensitivity to contrast media and dyes

This article updates current knowledge on hypersensitivity reactions to diagnostic contrast media and dyes. After application of a single iodinated radiocontrast medium (RCM), gadolinium-based contrast medium, fluorescein, or a blue dye, a hypersensitivity reaction is not a common finding; however,...

Full description

Saved in:
Bibliographic Details
Published inImmunology and allergy clinics of North America Vol. 34; no. 3; p. 547
Main Authors Brockow, Knut, Sánchez-Borges, Mario
Format Journal Article
LanguageEnglish
Published United States 01.08.2014
Subjects
Coloring Agents - adverse effects
Coloring Agents - classification
Contrast Media - adverse effects
Contrast Media - classification
Disease Management
Drug Hypersensitivity - diagnosis
Drug Hypersensitivity - epidemiology
Drug Hypersensitivity - etiology
Drug Hypersensitivity - therapy
Humans
Incidence
Risk Factors
Blue dyes
Dyes
Hypersensitivity
Fluorescein
Diagnostic procedure
Management
Gadolinium-based contrast media
Radiocontrast media
Online AccessGet more information

Cover

More Information
Summary:This article updates current knowledge on hypersensitivity reactions to diagnostic contrast media and dyes. After application of a single iodinated radiocontrast medium (RCM), gadolinium-based contrast medium, fluorescein, or a blue dye, a hypersensitivity reaction is not a common finding; however, because of the high and still increasing frequency of those procedures, patients who have experienced severe reactions are nevertheless frequently encountered in allergy departments. Evidence on allergologic testing and management is best for iodinated RCM, limited for blue dyes, and insufficient for fluorescein. Skin tests can be helpful in the diagnosis of patients with hypersensitivity reactions to these compounds.
ISSN:1557-8607
DOI:10.1016/j.iac.2014.04.002