Best Achievements in Translational and Basic Thyroidology in 2020

This review discusses articles published in 2020 that presented noteworthy achievements in translational and basic thyroidology. Previously unresolved questions about thyroid hormone receptor actions and signaling mechanisms were answered using various novel in vitro and in vivo models. Using high r...

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Bibliographic Details
Published inEndocrinology and metabolism (Seoul) Vol. 36; no. 1; pp. 36 - 40
Main Authors Cho, Sun Wook, Park, Young Joo
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Endocrine Society 01.02.2021
대한내분비학회
Subjects
Cryoelectron Microscopy
endocrine disruptors
gastrointestinal microbiome
Humans
receptors
Review
Signal Transduction
thyroglobulin
Thyroid Diseases
Thyroid Gland - physiology
thyroid hormone
thyroid neoplasm
Thyroid Neoplasms - therapy
내과학
Endocrine disruptors
Receptors, thyroid hormone
Thyroglobulin
Gastrointestinal microbiome
Thyroid neoplasm
Online AccessGet full text
ISSN2093-596X
2093-5978
2093-5978
DOI10.3803/EnM.2021.104

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Summary:This review discusses articles published in 2020 that presented noteworthy achievements in translational and basic thyroidology. Previously unresolved questions about thyroid hormone receptor actions and signaling mechanisms were answered using various novel in vitro and in vivo models. Using high resolution cryo-electron microscopy, the fine functional structure of thyroglobulin was demonstrated, and new insights into the pathogenesis of thyroid disease were achieved, with a focus on research into thyroid-disrupting chemicals and the gut microbiome. Novel therapeutic approaches were tried in the field of advanced thyroid cancer treatments.
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ISSN:2093-596X
2093-5978
2093-5978
DOI:10.3803/EnM.2021.104