Effect of the immunosuppressive regimen on the incidence of cytomegalovirus infection in 378 heart transplant recipients: A single centre, prospective cohort study

Highlights • CMV replication requiring pre-emptive therapy occurs in 40% of heart transplant recipients. • Older recipient age is a major risk factor for CMV infection. • The immune suppressive regimen strongly influences CMV infection. • CMV infection portends a rising incidence of pneumonia due to...

Full description

Saved in:
Bibliographic Details
Published inJournal of clinical virology Vol. 68; pp. 37 - 42
Main Authors Durante-Mangoni, Emanuele, Andini, Roberto, Pinto, Daniela, Iossa, Domenico, Molaro, Rosa, Agrusta, Federica, Casillo, Roberta, Grimaldi, Maria, Utili, Riccardo
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.07.2015
Subjects
Adult
Aged
Allergy and Immunology
Cytomegalovirus
Cytomegalovirus Infections - epidemiology
Cytomegalovirus Infections - pathology
Female
Heart Transplantation
Humans
Immunosuppression
Immunosuppressive Agents - adverse effects
Immunosuppressive Agents - therapeutic use
Incidence
Infectious Disease
Male
Middle Aged
Opportunistic infection
Opportunistic Infections - epidemiology
Opportunistic Infections - pathology
Prognosis
Prospective Studies
Risk Factors
Transplant
Transplant Recipients
Cytomegalovirus
Opportunistic infection
Immunosuppression
Prognosis
Transplant
Online AccessGet full text

Cover

More Information
Summary:Highlights • CMV replication requiring pre-emptive therapy occurs in 40% of heart transplant recipients. • Older recipient age is a major risk factor for CMV infection. • The immune suppressive regimen strongly influences CMV infection. • CMV infection portends a rising incidence of pneumonia due to opportunistic pathogens.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Undefined-1
ObjectType-Feature-3
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2015.04.017